DL - Final 6

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  1. What are the counseling pearls for Bactrim?
    • Finish entire prescription
    • May cause increased sensitivity to sunlight
    • Maintain adequate hydration
    • Potential for drug-drug interactions: warfarin, methotrexate, dofetilide
  2. What are the counseling pearls for Clindamycin?
    • Abdominal cramping and/or diarrhea is common – contact prescriber if severe
    • Do not refrigerate reconstituted oral solution (it will thicken), discard any unused portion after 2 weeks
    • Oral solution has foul taste
  3. What are the AE for Linezolid?
    • Nausea, diarrhea, headache
    • Bone marrow suppression (thrombocytopenia, >2 weeks)
    • Peripheral neuropathy, optic neuritis (rare, >4 weeks)
  4. What are the counseling pearls for Linezolid?
    • After reconstitution, store oral suspension at room temperature, discard any unused portion after 21 days
    • Potential for drug-drug interactions: serotonergic agents, pseudoephedrine
  5. Nitrofurantoin Counseling pearls:
    • Finish entire prescription (~7 days) – nitrofurantoin is NOT appropriate for short-course (3-day) UTI therapy
    • Take with food to decrease stomach upset
    • May cause urine discoloration (brown)
    • Contact prescriber if experience numbness, tingling or burning pain in hands, legs or feet
    • Report any shortness of breath, cough or fever to prescriber- Can cause pulmonary fibrosis
  6. Metronidazole Spectrum of activity:
    • Anaerobes, protozoa
    • Helicobacter pylori
  7. Metronidazole Common uses:
    • Bacterial vaginosis, trichomoniasis (STDs)
    • C. difficile colitis
    • H. pylori eradication
  8. Metronidazole Adverse effects:
    • Nausea, vomiting, diarrhea
    • Metallic taste disturbance
    • Peripheral neuropathy (rare), headache
    • Urine discoloration (black/brown/dark)
  9. Metronidazole Counseling pearls:
    • May take with food to decrease stomach upset
    • Metallic taste disturbance is common
    • May cause urine discoloration (harmless)
    • Avoid alcohol during therapy – with alcohol, may experience headache, flushing, nausea, vomiting, or abdominal pain (disulfiram-like reaction)
    • Potential for drug-drug interactions: warfarin
  10. What are the AE for All antibiotics?
    Allergy and C. diff
  11. What are the AE for Beta-lactams?
    Neutropenia, thrombocytopenia, seizures
  12. What are the AE for Macrolides?
    GI upset, thrombophlebitis (IV), P450 inhibition, bone marrow suppression
  13. What are the AE for Flouroquinolones?
    Photosensitivity, CNS effects, QT-prolongation, hypoglycemia, hyperglycemia
  14. What are the AE for Tetracyclines?
    NVD, photosensitivity, CNS effects
  15. What are the AE for Linezolid?
    Thrombocytopenia, optic neuritis, serotonin syndrome
  16. What are the AE for Clindamycin?
    N, V, D
  17. What are the AE for Metronidazole?
    Metallic taste, P450 inhibitor, disulfarim
Card Set:
DL - Final 6
2015-05-13 16:10:55
DL Final
DL - Final
DL - Final
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