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Give 6 functions of the Urinary system (kidneys!)(question 1)
- 1. Excretion (unwanted substances)
- 2. maintenance of water & electrolytes
- 3. pH regulation of body fluids
- 4. Production of hormones
- 5. Regulation of RBC's production
- 6. Regulation of blood glucose levels
- 7. Regulation of blood pressure volume & osmolarity
What are the 5 hormones that affect kidney reabsorption of sodium (Na), chloride (Cl) calcium (Ca) & water as well as the secretion of Potassium (K)
- 1. Angiotensin II
- 2. Aldosterone
- 3. Antidiuretic hormone
- 4. Atrial natriuretic peptide
- 5. Parathyroid hormone
Explain the Renin-Angiotensin-Aldosterone System (RAAS) (question 2)
blood pressure - Kidney
cells secrete Renin
from the liver
into Angiotensin I
3. Angiotensin converting enzyme
) secreted by the lungs
(proximal convoluted tubules) converts Angiotensin I
into Angiotensin II
- The active form of the hormone
- 4. Angiotensin II (a blood protein):
- Triggers vasoconstriction
- Triggers pituitary gland to release ADH (vasopressin)
- Stimulates adrenal cortex to produce Aldosterone.
- 5. Aldosterone:
- Causes the kidneys to retain sodium (Na) and excrete Potassium (K)
This causes water retention
, increasing blood volume
and blood pressure
How does Atrial Natriuretic Peptide (ANP) work to decrease blood volume/pressure? (question2)
is released from the heart when there is a large increase in blood volume/pressure.
- 1. It inhibits reabsorption of sodium (Na+) & water in the renal tubules
- 2. It suppresses anti-diuretic hormone & aldosterone.
This results in an increased excretion
(Na) in the urine and increased urine output
which decreases blood volume & pressure
How does Parathyroid Hormone (PTH) work on the kidneys?
LOW blood calcium stimulates the parathyroid glands to release parathyroid hormone:
PTH stimulates the kidneys tubules to reabsorb more calcium and inhibits phosphate reabsorption.