cell biology nbeo.txt

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cell biology nbeo.txt
2015-05-28 23:15:51
cell biology optometry NBEO

cell biology optometry NBEO
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  1. What is the order of DNA replication?
    • Transcription = DNA to mRNA
    • Translation = mRNA to protein
  2. What class of drugs attack 30s ribosomes?
    • Aminoglycosides
    • Tetracyclines
  3. What class of drugs attack 50s ribosomes?
  4. Where are steroids produced?
    Adrenal cortex
  5. What part of the cell is affected in tay sach's disease?
  6. What part of the cell is affected in leber's hereditary optic neuropathy and kearns-sayre syndrome?
  7. What is the main ion inside the cell?
  8. What is the ratio of Na/K pumped out of the cell?
  9. What is the main ion outside the cell?
  10. What is depolarization?
    Inside of cell becomes more positive = action potential
  11. What is hyperpolarization?
    Inside of cell becomes more negative = stalled action
  12. What are the concentrations of intracellular, extracellular compartments and plasma in the body?
    25L, 12L, 3L
  13. What do A1 receptors do?
    • A+ MUScles are drinking their calcium
    • Increase intracellular calcium (together with muscarinic)
  14. What are the locations of A1 receptors?
    • Radial iris dilator
    • Vascular SM
    • GI sphincters
  15. What do A2 receptors do?
    • Decrease cAMP
    • Inhibitory response in heart, elsewhere = sympathetic
  16. what do B1 receptors do?
    • Stimulate adenylyl cyclase
    • Increase cAMP
  17. Where are the locations of B1 receptors?
    • Heart
    • Salivary glands
    • Adipose tissue
    • Kidneys
    • NPCE
  18. What do B2 receptors do?
    Increase cAMP
  19. What are the locations of B2 receptors?
    • Bronchioles
    • GI tract
    • Bladder wall
    • Vascular SM
    • TM
    • CB
  20. What is the only receptor to act on Na/K channels?
    • Nicotinic
    • A NaK for being unique
  21. What are zonula occludens?
    • Impermeable Tight belt junctions around entire cell
    • BAB & BBB
  22. What are zonula adherens?
    Junctions that allow for intercellular passage
  23. What are macula occludens?
    Impermeable spot welds
  24. What are gap junctions?
    Channels connected to other channels for rapid electrical transfer = HDMI port
  25. What type of cells are binuclear?
    • Hepatocytes
    • Cardiac muscle
    • Urinary tract epithelial cells
  26. What type of cells are multinuclear?
    • Osteoclasts
    • Skeletal muscle
  27. What type of cells are anuclear?
  28. What is contained within the nucleolus?
    Dense chromatin
  29. What does the nucleolus do?
    Responsible for production of rRNA
  30. What is rRNA?
    • Found in ribosomes
    • Responsible for protein translation
  31. What is tRNA?
    • Responsible for translation
    • Which is transfer of amino acids to a growing protein
  32. What do hepatocytes do?
    • Storage and breakdown of glycogen
    • Detox of lipid soluble drugs
  33. What do ribosomes do?
    Manufacture protein
  34. What does smooth er do?
    • Lipid and steroid production
    • Produces fatty acids
  35. What is rough ER responsible for?
    Protein synthesis
  36. What does the golgi apparatus do?
    • Modify and package proteins from rough ER to outside of cell
    • (fedex)
  37. What do lysosomes do?
  38. What does the mitochondria do?
    Produces ATP
  39. What do microtubules do?
    Intercellular motility
  40. What do intermediate filaments do?
    • Act as a super highway to/from nucleus
    • Gives resistance against external pressure on cell
  41. What is the intracellular charge at equilibrium?