Ch 20 1 Pharm

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Author:
jld15
ID:
303926
Filename:
Ch 20 1 Pharm
Updated:
2015-06-10 18:18:29
Tags:
20 Pharm
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Description:
Ch 20 1 Pharm
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The flashcards below were created by user jld15 on FreezingBlue Flashcards. What would you like to do?


  1. Adrenergic Drugs
    • stimulate activity at NE synapses – adrenergic agonists
    • inhibit NE influence – adrenergic antagonists
    • Sympathomimetic
    • Sympatholytic
  2. Alpha-1 receptors
    • Vascular smooth muscle
    • Vasoconstriction
    • ----Increase BP by increasing peripheral vascular resistance
  3. Alpha 1 receptor Agonist use
    Hypotension
  4. Alpha 1 agonists drugs
    • Meptenteramine (Wyamine)
    • Methoxamine (vasoxyl)
    • Oxymetazoline (Afin, Visine)
    • Phenylephrine (Neo-synephrine)
  5. Mephenteramine (Wyamine)
    • Maintain/restore BP during hypertensive episodes
    • Intravenous/intramuscular
  6. Methoxamine (vasoxyl)
    • Increase/maintain BP in severe, acute hypotension
    • Intramuscular for rapid onset
  7. Oxymetazoline (Afin, Visine)
    • Nose drops, nasal sprays to decrease nasal congestion through vasoconstriction; eye drops
    • High doses cause hypotension
  8. Phenylephrine (Neo-synephrine)
    • Terminate supraventricular tachycardia
    • Treat nasal congestion
    • In over the counter decongestants
  9. Alpha 1 receptor Antagonist use
    Hypertension
  10. Alpha-2 receptors synapse in
    CNS
  11. Alpha 2 Agonist uses
    • Hypertension
    • Spasticity
    • Presynaptically: Decrease NE release from presynaptic terminal
    • Postsynaptically: inhibit neuronal excitation
  12. Alpha 2 agonists
    • Clonidines (Catapres, Duraclon)
    • Guanabenz (Wytensin)
    • Methylodopa (Aldomet)
    • Tizanidine (Zanaflex)
  13. Clonidines (Catapres, Duraclon)
    • Antihypertensive, analgesic
    • ----decreases sympathetic discharge to the heart and vasculature
    • Antianxiety
  14. Guanabenz (Wytensin)
    • Decrease BP
    • Similar to clonidines

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