Ch 20 2 Pharm

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Author:
jld15
ID:
303927
Filename:
Ch 20 2 Pharm
Updated:
2015-06-10 18:19:13
Tags:
20 Pharm
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Description:
Ch 20 2 Pharm
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  1. Methylodopa (Aldomet)
    • Antihypertensive
    • ----Inhibits central adrenergic receptors
    • Similar to clonidines
  2. Tizanidine (Zanaflex)
    • Spasticity
    • Similar to chlodines but less vasomotor effects
    • Less likely to cause hyper tension
    • Decreases excitability of alpha motor neuron (decreasing spasticity)
  3. Alpha 2 Antagonist
    No significant clinical use
  4. Beta-1 receptors
    Heart (increased heart rate)
  5. Beta 1 Agonist treat
    Cardiac decompensation
  6. Beta 1 Antagonists treat
    • Hypertension
    • Arrhythmias
    • Heart failure
    • Angina
    • Prevention from reinfarction
  7. Beta-2 receptors
    • Bronchioles
    • Uterus
  8. Beta 2 receptors Agonist
    • Prevent bronchospasm
    • Prevent premature labor
  9. Beta 2 Antagonist
    No significant clinical use
  10. Alpha-1 Selective Agonists treat
    • Bind to and activate alpha-1 receptors
    • Vasoconstrictive properties
    • ----Increases blood pressure
    • --------Mephenteramine
    • --------Methoxamine
    • --------Phenylephrine
    • ----Decrease nasal congestion
    • --------Oxymetazoline (Afrin)
    • --------Pseudoephedrine (Sudafed)
  11. Alpha- 2 Selective Agonists treat
    • Hypertension
    • ----Clonidine
    • ----Guanabenz
    • ----Methyldopa
    • Spasticity
    • ----Tizanidine
  12. Alpha 2 Selective Agonists Adverse effects
    • Minor
    • Moderate
  13. Beta-1 Selective Agonists
    Used primarily to increase cardiac output and increase cardiac function
  14. Beta 1 selective agonists drugs
    • Dobutrex (dobutamine)
    • Intropin (dopamine)

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