Hemo 2

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Author:
jld15
ID:
304017
Filename:
Hemo 2
Updated:
2015-06-14 12:33:16
Tags:
Hemo
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Description:
Hemo 2
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  1. Treatment and Prognosis of Anemia
    • Treat underlying cause with Supplemental therapy
    • ----Iron deficiency child bearing
    • ----Blood transfusion bc surgery
    • ----Kidney disease: given EPO
    • ----Epogen stimulate RBC production
    • Androgens to stimulate RBC’s
    • Splenectomy
    • ---- RBC not destroyed
    • EPO (erythropoietin)
  2. Fe deficiency anemia
    Increased HR with little work so May not tolerate endurance program
  3. Polycythemia Vera (erythrocytosis)
    • Myeloproliferative-
    • ----Neoplastic disease of the bone marrow stem cell where bone marrow doesn’t know when to stop making RBC
    • Erythroid cell Continue to grow, don’t know when to stop
    • Risk increases with
    • ----Age
    • ----Men
    • ----Radiation exposure?
  4. Polycythemia Signs and Symptoms
    • Increased viscosity
    • ----Bc too many RBC
    • ----Heart have to work harder (HR?)
    • ----Can lead to heart failure
    • Hct exceeds 60%
    • Skin discoloration
    • Gout
    • ----Arthritis due to build up of uric acid
    • Insidious onset
    • ----Don’t know it is happening until get blood test
  5. Polycythemia Dx
    • Uric acid test
    • RBC count
  6. Absolute versus relative polycythemia
    • Absolute: definitive increase in RBC but same volume
    • Relative: RBC stay the same, decrease in blood volume
  7. Polycythemia Treatment
    • Reduce blood volume
    • Chemotherapy
    • ----Hydroxyuria: Attacks RBC to decrease number circulating
  8. Polycythemia Prognosis
    • Good with treatment
    • Risk of stroke, MI, thromboembolism
    • *GOAL IS TO PREVEN CLOTTING!
  9. Leukocytes
    • Granulocytes
    • ----Basophils
    • ----Eosinophils
    • ----Neutrophils (PMN)
    • --------Bacteria
    • --------First line of defense
    • --------Contain lysine agent to break down foreign material
    • Monocytes
    • ----Immature and Form macrophages when attach to bacteria
    • Lymphocytes
    • ----Assist in the immune response
  10. Leukocytosis
    • Transient increase in leukocytes
    • Treat underlying cause
    • ----Caused by corticosteroids (prednisone)
    • Prognosis dependent on underlying cause
  11. Leukopenia
    • Reduction in the number of leukocytes
    • Increase risk for infectious disease
    • Treatment directed at the cause
    • ----if chemo problem Neupogen: stimulates WBC formation
  12. Basophilia
    • Myeloproliferative disorders
    • Increased number of basophils
    • ----Problem with bone marrow
    • ----Can see with polysythemiara and allergic reactions
  13. Eosinophilia
    • Increase in eosinophills
    • Seen with allergic reactions and asthma
  14. Neutrophilia
    • Granulocytosis
    • ----Increased in granulocytes
    • Seen in Inflammation and Infection

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