Hemo 4

Card Set Information

Author:
jld15
ID:
304028
Filename:
Hemo 4
Updated:
2015-06-14 14:07:02
Tags:
Hemo
Folders:

Description:
Hemo 4
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user jld15 on FreezingBlue Flashcards. What would you like to do?


  1. Disseminated intravascular coagulation
    • Clotting and hemorrhage occur simultaneously bc All clotting factors used up
    • Common after:
    • ----Shock
    • ----Sepsis
    • ----Leukemia
    • ----Massive trauma
    • Less obvious signs
    • ----Petechiae
    • ----Cold, mottled digits
  2. Intrinsic vs extrinsic DIC
    • intrinsic
    • ----endothelium
    • extrinsic
    • ----damage to the tissue around it
  3. Management of DIC
    • Dx by clinical presentation and lab work
    • Treatment based on underlying cause
    • Morbidity and mortality
    • ----Independent predictor in pt with sepsis of severe trauma
    • You don’t work with is pt until stabilized
  4. Sickle Cell Disease
    • Generic term for a group of inherited autosomal recessive disorders
    • ---Needs to come from both parents
    • Abnormal hemoglobin in the erythrocyte
  5. Pathophysiologic features of sickle cell disease
    • Chronic hemolytic anemia
    • ----Becomes sickle opposed to biconcave after o2 leaves
    • ----Only lasts 10-20 days now opposed to 120 days (destroyed before needs met)
    • Vasoocclusion
    • ----Can stick to other cells and become a clot preventing good cells from getting through
  6. Risk Factors SCD
    • SCD is characterized by “crises”
    • ----Early destruction of the abnormal cells and obstruction of blood flow to the tissues
  7. SCD Episodes precipitated by:
    • Infection
    • Dehydration
    • Fatigue
    • Acidosis
    • Physical exertion
    • High altitude
  8. Clinical Signs and Symptoms SCD
    • Sickled erythrocytes
    • ----Hemolytic anemia
    • ----Occlude microvasculature
    • Crises or episodes
    • ----Vasoocculsive or thrombotic
    • ----Aplastic
    • --------Bone marrow stops producing blood cells for a certain period of time
    • ----Sequestration
    • ----Hyperhemolytic
    • ----Ultra destruction of RBC
    • Pain
    • ---Thrombosis
    • Tissue damage
  9. SCD Complications
    • Neurologic: stroke
    • Hand-foot syndrome: swollen
    • End stage renal disease
    • Bacterial infections
    • Iron overload
    • Chronic leg ulcers
    • Retinopathy
  10. SCD Management
    • Universal screening every newborn
    • Bone marrow transplant
    • ----Tough to find match donors; High risks
    • Supportive care
    • ----Exercise btwn crises, ROM
    • ----Stay hydrated
    • ----Pain will limit exercise
  11. SCD Prognosis
    • No cure
    • Treat the signs and symptoms
    • Hydroxyuria (cancer med) decrease number of sickling cycles prolonging longevity
  12. Sickle Cell Trait
    • Heterozygous condition (from one partent)
    • Rarely symptomatic
    • Sudden death associated with exercise
  13. Thalassemias
    • Group of inherited chronic hemolytic anemia's
    • ----Destroy RBC
    • 1. Fragile erythrocytes – target cells (Destroyed more easily)
    • 2. Alpha or Beta
    • ----Depending on which chain on Hb is missing
    • 3. Minor
    • ----Mild to no symptoms/treatment
    • 4. Major: Cooley’s anemia
    • ----Large number of fragile RBC leading to lots of symptoms
    • ----Need blood transfusions every few weeks
    • ---Blood monitored
    • ----May need elation (Remove Fe)

What would you like to do?

Home > Flashcards > Print Preview