Card Set Information
Prototype for opiates
What is the physiology of pain?
Injury > Arachidonic Acid >Cyclooxygenase > prostaglandins (Vasodilation) > Activating Pain receptors
Injury > Bradykinin (Vasodilation) > Activating Pain Receptors
What is exogenous pain relief
Things we take in to relieve pain
What is endogenous pain relief
System of opioid peptides
: endorphins, seratonin, GABA
Things our body can do to relieve pain
What are the two types of pain we look for?
What to look for during pain assessment
relation to time, activity
What are the 3 categories of pain management?
: Acetaminophen, Salicylates, NSAIDs
: Benzodiazepine, TCA, Corticosteroids
What is the therapeutic effect of opiates?
interferes with pain impulses thereby decreasing pain
What are the ADE of Opiates?
: decreases respiratory rate, sedation, dizziness
Depress GI Tract
: N/V, Constipation
Alters psychological response to pain
What are the route of administration for Opiates?
PCA (Patient Controlled Analgesia)
What is common clinical use for opiates?
Severe-Moderate pain relief
acute pulmonary edema
severe non-productive cough (CODEINE, ANTITUSSIVE)
What's an antitussive?
cough suppressant (codeine)
When do you use opiates cautiously?
pt has respiratory depression
Chronic lung disease
kidney or liver failure
increased intracranial pressure
What are infrequent uses for opiates?
invasive diagnostic test
labor and delivery
What is an opiate antagonist?
counteracts opiates by binding to opiate receptors
*Not a CNS stimulant*
What is important for a drug user when administering an opiate antagonist?
monitor for withdrawal symptoms
When is it considered opiate abuse?
When it is being used for mind-altering
What are some symptoms of opiate abuse?
myosis (constricted pupils)
What are treatments for opiate abusers?
will still be addicted, but will be more productive