autonomic nervous system

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Author:
BodeS
ID:
305057
Filename:
autonomic nervous system
Updated:
2015-07-16 01:28:12
Tags:
pharmacology
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Description:
drugs in parasympathetic and sympathetic nervous systems
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  1. Clonidine
    • trade name: Catapres
    • ID: antihypertensive
    • adrenergics [CNS]
    • sympathetic agonist
    • routes: PO, transdermal
    • treat: mild to severe hypertension
    • ADHD
    • target: alphaagonist
    • stimulate alpha adrenergic receptors
    • decrease sympathetic activity
    • action: block Nori
    • location: pre-synapse junction @ CNS 
    • contraindicated: anticoagulant therapy
    • risk: CNS-drowsy
    • depression
    • anxietyhallucinations
    • nightmares
    • CV- AV node block
    • hypotension
    • bradycardia
  2. Atropine
    • generic name:  Atropine 
    • ID: antiarrhythmics
    • anticholinergics
    • sympathomimetics
    • parasympatholytics
    • route: IM, IV
    • treat: Presurgery-  
    • to reduce salivation and bronchial secretions 
    • to minimize bradycardia during intubation
    • GI plyorospasm and spastic conditions
    • Nephrotic- urethral and biliary colic
    • target: blocks muscarinic receptors
    • inhibit ACh uptake @ PNS
    • decrease parasympathetic activity
    • mimic sympathetic activity
    • action: stimulate smooth muscle 
    • inhibit secretory glands
    • location: postganglionic sites @ PNS
    • contraindicated: heart disease
    • angle-closure glaucoma
    • enlarged prostate
    • risk: urinary retention
    • constipation
  3. Epinephrine
    • trade name: Adrenaline
    • ID: vasopressors
    • bronchodilators
    • antiasthmatics
    • adrenergics
    • route: IV, IM
    • target: beta1 agonist
    • bind to beta-adrenergic receptor sites
    • release Nori into synapse
    • release Epi into blood
    • treat: asthma
    • anaphylaxis
    • cardiac arrest
    • action: beta1-vasopressors 
    • beta2- bronchodilator
    • location: nori- synapse
    • epi- adrenal medulla
    • contraindication: paradoxical bronchospasm
    • risk: seizure
    • hyperglacemia (beta2- glycogenolysis)
  4. beta2 vs. asthma
    • action: agonist- bronchodilation
    • risk: antagonist- bronchospasm
    • indicated: respiratory disease
    • contraindicated: asthma
  5. selective vs. nonselective beta-blockers
    • selective: beta1 heart receptors
    • treat: BP
    • HTN 
    • indicated: beta2 lung receptors
    • asthma
    • respiratory disease
    • risk: overuse causes non-selective activity
    • chance of bronchospasm
    • contraindicated: long-term use of selective beta-blockers
  6. adrenergic drugs
    SIDE EFFECS
    • Clonidine
    • Epinephrine
    • Levophed
    • Albuterol

    • PROMOTE
    • Sweat
    • Lacrimate
    • Urinate
    • Defecate
    • Salivate
  7. anticholingergic drugs
    SIDE EFFECTS
    Atropine

    • SUPPRESS
    • Sweat
    • Lacrimate
    • Urinate
    • Defecate
    • Salivate
  8. albuterol
    • trade name: Proventil
    • ID: adrenergic
    • bronchodilator
    • vasodilator
    • adrenal medulla hormone
    • cathecholemine
    • route: PO [inhaler]
    • treat: asthma
    • target: beta2-receptors
    • action: beta2-adrenergic agonist
    • decrease smooth muscle contraction 
    • increase relaxation in airways
    • glucogenolysis
    • location: lungs
    • contraindication: non-selective beta-blockers risk: paradoxical bronchospasm
    • children-hyperactivity
    • cross-sensitivity to hypertension
    • diabetes
    • glaucoma
  9. beta1 agonist
    drug
    drug: Epinephrine
  10. alpha2 agonist
    drug
    drug: Clonidine
  11. beta2 agonist
    drug
    drug: albuterol [Proventil]
  12. alpha1 agonist
    drug
    drug: norephinephrine [Levophed]
  13. beta1 antagonist
    drug
    SIDE EFFECTS
    • drug: Propranolol
    • Atenolol
    • SIDE EFFECTS: slow heart rate
    • lower BP
    • decrease Renin-Angiotensin-Aldosterone
  14. albuterol
    SIDE EFFECTS
    • contraindication: non-selective beta-blockers risk: paradoxical bronchospasm
    • children-hyperactivity
    • cross-sensitivity to hypertension
    • diabetes
    • glaucoma

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