Gastrointestinal

Card Set Information

Author:
BodeS
ID:
305116
Filename:
Gastrointestinal
Updated:
2015-07-13 17:26:26
Tags:
pharmacology
Folders:

Description:
drugs and poop
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  1. bulk-forming
    • drug name: Metamucil
    • ID: fiber
    • H2O
    • indicated: long-term use
    • elderly patients
    • low-fiber diet
    • action: stimulates peristalsis
    • side effects: pull H2O into intestinal lumen
    • contraindicated: dysphagia
    • risk: fecal impaction
  2. stool-softener
    • drug name: Colase
    • ID: surfactant laxative
    • detergent
    • indicated: prevention
    • constipation
    • action: reduce surface tension of fecal mass
    • allow H2O to penetrate into stool
    • mix fat and water in stool 
    • contraindicated: high BP
    • risk: sodium restriction
  3. saline
    • drug name: Milk of Magnesia
    • ID: saline laxative
    • sodium
    • indicated: colonoscopy
    • action: osmotic retention
    • distend colon
    • stimulate peristalsis
    • contraindicated: sodium restriction
    • congestive heart failure
    • kidney disease
    • risk: electrolyte imbalance
  4. stimulant
    • drug name: Dulcolax
    • ID: cathartic 
    • strong laxative
    • indicated: pre-surgery
    • action: irritate HI mucosa
    • pull H2O into bowel lumen
    • contraindicated: substance abuse
    • risk: dependence
    • electrolyte/acid imbalance
  5. lubricant
    • drug name: Fleet
    • ID: mineral oil
    • indicated: enema
    • action: H2O retention
    • contraindicated: regular use 
  6. Antacid
    • drug name: Maalox
    • Tums
    • ID: alkaline substances
    • magnesium hyroxide
    • calcium carbonate
    • treat: GERD
    • heartburn
    • action: coating
    • neutralize gastric acid
    • decrease pepsin production
    • location: stomach
    • risk: diarrhea
    • constipation
  7. GERD
    • ID: gastroesophageal reflex disease
    • stomach disorder
    • risk: hiatal hiatus
    • erosive esophagitis 
    • ulcer
    • treatment: antacids
    • histamine 2 blockers
    • proton pump inhibitors
  8. PUD
    • ID: peptic ulcer disease
    • stomach disorder
    • risk: stomach ulceration
    • duodenal ulcerations
    • treatment: antibiotic [h.pylori]
    • histamine 2 blocker
    • proton pump inhibitor
  9. Histamine 2 blocker
    • famotidine [Pepcid]
    • cimetidine [Tagamet]
  10. proton pump inhibitors
    omeprazole [Prisolec]
  11. histamine 2 receptors
    • parietal cells in stomach 
    • produce HCl
  12. Histamine H2 Antagonists
    • official name: famotidine
    • cimetidine
    • trade name: Pepcid
    • Tagamet
    • ID: antiulcer agent
    • H2 antagonist
    • route: PO
    • IV
    • treat: PUD [gastric/duodenal] 
    • GERD
    • target: histamine 2 receptors 
    • parietal cells
    • action: bind to histamine
    • block H2 receptors in stomach
    • decrease gastric acid secretions
    • Tagamet-inhibit the CYP450 enzymes
    • location: stomach
    • contraindicated: hypersensitivity to alcohol
    • Tagamet: drug-drug sensitivity
    • risk: aplastic anemia
    • hepatitis
  13. omeprazole
    • trade name: Prilosec
    • ID: antiulcer agent
    • proton pump inhibitor
    • route: PO
    • treat: GERD
    • PUD [gastric/duodenal]
    • erosive esophagitis
    • target: proton pump in stomach
    • action: bind to pump
    • bind to enzyme on parietal cells in stomach
    • inhibit gastric secretion
    • contracindication: drug-drug sensitivity
    • CYP450 
    • Tagamet
    • risk: superinfection
  14. antiulcer agents
    • H2 antagonists
    • proton pump inhibitor
  15. Tagamet 
    drug-drug sensitivity
    • ID: inhibit CYP450 enyzme
    • drugs affected: benzodiazepines
    • beta-blockers
    • SSRI
    • metformin
    • sulfonylureas

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