Basic Principles of Immunology
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From the following, identify a speciﬁc component of the adaptive immune system that is formed in response to antigenic stimulation: A. Lysozyme
C. Commensal organisms
- Immunoglobulin is a speciﬁc part of the adaptive immune system and is formed only in response to a speciﬁc antigenic stimulation. Complement, lysozyme, and commensal organisms all act nonspeciﬁcally as a part of the adaptive immune system. These three components do not require any type of speciﬁc antigenic stimulation.
Which two organs are considered the primary lymphoid organs in which immunocompetent cells originate and mature?
A. Thyroid and Peyer’s patches
B. Thymus and bone marrow
C. Spleen and mucosal-associated lymphoid tissue (MALT)
D. Lymph nodes and thoracic duct
- The bone marrow and thymus are considered primary lymphoid organs because immunocompetent cells either originate or mature in them. Some immunocompetent cells mature or reside in the bone marrow (the source of all hematopoietic cells) until transported to the thymus, spleen, or Peyer’s patches, where they process antigen or manufacture antibody. T lymphocytes, after originating in the bone marrow, travel to the thymus to mature and diﬀerentiate.
What type of B cells are formed after antigen stimulation?
A. Plasma cells and memory B cells
B. Mature B cells
C. Antigen-dependent B cells
D. Receptor-activated B cells
- Mature B cells exhibit surface immunoglobulin that may cross link a foreign antigen, thus forming the activated B cell and leading to capping and internalization of antigen. The activated B cell gives rise to plasma cells that produce and secrete immunoglobulins and memory cells that reside in lymphoid organs
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