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What does the adrenal cortex produce?
- Sex hormones
- Mineral corticoid
What does the mineral corticoid steroid produce? What does it do?
- Conserves NA and H2O
- Eliminates K
Describe Addison's Disease
Decreased Aldosterone > decrease NA, H2O, Increase K
Describe Cushing's Disease
increased aldosterone > increase NA, H2O, decrease K
What is the gucocorticoids prototype?
What does prednisone do to the CHO Metabolism?
What does prednisone do to the inflammatory system?
What does prednisone do to the Nervous System
euphoria, mood change, aggression
What does prednisone do to the GI
What does prednisone do to the Protein Metabolism
What does prednisone do to theFluid and Electrolyte
What does prednisone do to the Respiratory system
- Breath easier
- increases bronchodilator, stabilizes mast cells
What type of dose is used in replacement therapy?
why type of dose is used in a therapeutic doses?
- larger doses
- extension of the physiological effects
What can you do to decrease ADEs of steroids
- local use (topically, inhaler)
- short course
- taper doses
- ADT or double dose every other day (for pts that need steroids for chronic use)
- give in morning
ADT-alternate day therapy
Are steroids a cure or palliative?
What is the prototype of steroids used for Anti-inflammatory
What is the prototype of steroids used for Neurological
What is the prototype of steroids used for Allergic Disorders
What is the prototype of steroids used for Endocrine disorder
What is the prototype of steroids used for GI
What is the prototype of steroids used for immunosuppressant
What is prednisone used for?
What are contraindications of glucocorticoids?
- systemic fungal infection
Use glucocorticoids cautiously in
- Risk for infection/with infection: (immunosuppressant)
- DM: Increases BS
- Peptic Ulcer
- Increased BP, CHF: increased aldosterone can cause increase in holding onto water
- Renal insufficiency
What should you give glucocorticoids with?
Milk or Food
Nursing Dx with alt in body image
- Moon Face
- round belly
- skinny legs
- *generally temporary*