What is the most accurate measure of nutritional status?
Labs indicative for dehydration
Lab indicative for pressure ulcers
Labs for anemia screening
Serum albumin normal levels:
Where is serum albumin made?
Liver @ 9-12 g/day
~60% is located in extravascular space
What does albumin do?
Maintain colloid osmotic pressure, facilitates transportation of substances, and functions as afree-radical scavenger
Serum albumin levels are related to
visceral protein levels (blood and organs)
What does serum albumin have to do with colloid osmotic pressure?
A form of osmotic pressure exerted by proteins, notably albumin, in a blood vessel's plasma (blood/liquid) that usually tends to pull water into the circulatory system. Proteins are the only dissolved substance in the plasma (2-3 x higher) and interstitial fluid (lower levels) that do not diffuse readily through the capillary membrane exerting osmotic pressure
Hypoalbuminemia is associated with
Serum albumin levels above normal range are likely due to
Serum albumin has a long or short half life
Serum albumin levels ______ reflect current protein intake
Serum transferrin normal levels:
Serum transferrin levels are related to
visceral protein levels
What is the serum transferrin level controlled by
iron storage pool
Serum transferrin levels rise with
Serum transferrin levels can be determined from
TIBC -- total iron binding capacity
TTHY transthyretin, PAB prealbumin normal levels:
TTHY transthyretin, PAB prealbumin has a long or short half life
TTHY transthyretin, PAB prealbumin picks up changes in protein status _______
What is the best protein lab to evaluate?
TTHY transthyretin, PAB prealbumin
Retinol-binding protein (RBP) normal levels:
Retinol-binding protein (RBP) circulates with...
Retinol-binding protein (RBP) has a half life of how long
shortest half life: 12 hours
What does Retinol-binding protein (RBP) do?
Binds and transports retinol
What is Hematocrit (Hct)?
volume of packed cells in whole blood
What is the normal Hematocrit (Hct) for men, women, and pregnancy?
What is Hemoglobin (Hb)?
Iron-containing pigment in RBC
Normal levels of Hemoglobin (Hb) for men. women, and pregnancy?
M: 14-17 mg/dl
W: 12-15 mg/dl
Pregnancy: 11 mg/dl or less
Hemoglobin and Erythrocyte's relationship
Hemoglobin is found in the cytoplasm of a Erythrocyte cell (RBC). The Hemoglobin is the protein that contains iron and transports oxygen to the body giving Erythrocytes their red color.
Where are Erythrocytes produced?
Serum Ferritin normal levels for males and females:
M: 12-300 ng/ml
F: 10-150 ng/ml
What does the serum ferritin levels indicate?
Size of iron storage pool
Serum creatinine normal levels:
0.6 - 1.4 mg/dl
Serum creatinine is related to
Serum creatinine levels measure
Serum creatinine levels may indicate
renal disease, muscle wasting
Creatinine height index (CHI) normal %
Creatinine height index (CHI) formula:
ratio of creatinine excreted/24 hours to height
What does creatinine height index (CHI) measure?
estimates LBM -- somatic protein
What does 60-80% creatinine height index (CHI) level mean
mild muscle depletion
Blood urea nitrogen (BUN) normal levels:
Blood urea nitrogen (BUN) related to
related to protein intake
Blood urea nitrogen (BUN) an indicator of
BUN: creatinine ratio
Blood urea nitrogen (BUN) levels need to be under _____ for renal patients
Urinary creatinine clearance levels:
115 +/- 20 ml/minute
Urinary creatinine clearance measures what?
GFR -- glomerular filtration, renal function
Total lymphocyte count (TLC) levels:
<2700 cells/cu mm
What does total lymphocyte count (TLC) measure?
Total lymphocyte count (TLC) moderate depletion levels:
Total lymphocyte count (TLC) severe depletion levels:
When do total lymphocyte count (TLC) decrease?
in Protein-Energy Malnutrition (PEM)
C-reactive protein (CRP) is the marker of what?
acute inflammatory stress
as C-reactive protein levels decline, it indicates....
when nutritional therapy would be beneficial
Free erythrocyte protoporphyrin (FEP) is the direct measure or