Unstable Angina (UA)/ Non-ST Elevation Myocardial Infarction (NSTEMI)
- Results from reduction in myocardial O2 supply due to rupture or erosion of an atherosclerotic coronary plaque leading to thrombosis, inflammation, and vasoconstriction (<50% stenosis).
- Dx: 1. Angina at rest, 2. Chronic angina pectoris that becomes more frequent and easily provoked, 3.New-onset angina
- Adjuncts: Hemodynamic instability or CHF (S3 gallop, jugular venous distention, pulmonary rales, peripheral edema), ST depression, deep/symmetrical T-wave inversions
- Tx:1. Bed rest, 2. Supplemental O2, 3. analgesia, 4.Beta blocker, 5. SL NTG, 6. Aspirin/clopidogrel & 48 hours of IV heparin