heart failure

  1. positive inotropic
    increase heart contraction
  2. positive chronotropic
    increase HR
  3. positive dromotropic
    accelerate cardiac conduction
  4. ACE inhibitors
    • -Pril
    • inhibits aldosterone secretion> prevents H20 and Na reabsorption > diuresis > decreases the preload
  5. ACE inhibitor A/E
    • hyperkalemia
    • DRY COUGH!
    • do not take when pregnant
  6. Angiotensin II receptor blocker
    • -Sartan
    • vasodilator > Decrease SVR
    • No cough
  7. B-type natriuretic peptides
    • Nesiritide
    • Vasodilator
    • increases CO
    • used for life threatening HF
  8. B-type natriuretic peptide A/E
    • hypotension
    • dysrhythmias
    • headache
    • abdominal pain
  9. phosphodiesterase inhibitors
    • -Rinone
    • +inotropic drug
    • vasodilator
    • makes the heart more effective
    • not for severe valuvlar disease and diastolic HF
  10. phosphodiesterase inhibitors A/E
    • thrombocytopenia
    • dysrhythmias (ventricular)
    • hypotension
    • angina
    • hypokalemia
    • tremors
  11. cardiac glycosides
    • Digoxin: increases heart contractility, decreases HR and conductivity
    • increase SV
    • diuresis
  12. digoxin
    • 0.5 - 2 ng/ml
    • low K levels cause digoxin toxicity
    • drug levels and electrolytes must be monitored
    • wait for labs (afternoon)!!
  13. cardiac glucosides A/E
    • dysrhythmias 
    • increase/decrease HR
    • Head ache
    • fatigue
    • confusion
    • colored halo : flickering light vision
    • N/V
    • diarrhea
  14. digoxin toxicity
    • digoxin level >10ng
    • yellow vision
    • hyperkalemia (5mEq)
    • cause heart dysrhythmias
    • antidote: digoxin immune Fab
  15. hold meds when HR is
    under 60 and above 100
  16. nitrates
    • Nitro-, isosorbide
    • vasodilator   
    • prevention and treatment of angina
  17. Nitrate A/E
    • HA, so take Tylenol
    • tachycardia
    • hypotension: LIE DOWN!
    • tolerance, so take patch off at bedtime
  18. Beta-Blocker
    • -lol
    • decrease HR
    • decrease contractility
    • block harmful effects of catecholamines after an MI
    • long term prevention of angina (not immediate)
  19. beta blocker A/E
    • bradycardia
    • hypotension
    • wheezing!
    • impotence
    • dyspnea
    • drosiness
  20. calcium channel blockers
    • -ine, verapamil, diltiazem
    • vasodilation > decrease SVR > decrease the workload on heart > decrease myocardial 02 demand
  21. Calcium channel blockers A/E
    • hypotension
    • palpitations
    • Nausea
  22. report a wt gain of
    2 lbs in a day, 5 lbs in a wk
  23. avoid alcohol and hot tubs because
    the cause hypotension > fainting
  24. expected outcome associated with digoxin
    decreased HR
  25. pts should avoid this food with digoxin
    wheat bran. (bran decreases drug absorption)
  26. nurse should assess what when receiving a positive inotropic drug.
    • lung sounds
    • daily weights
    • pulse and serum electrolytes (bradycardia, hypokalemia)
Author
athors766ns
ID
307564
Card Set
heart failure
Description
pharm
Updated