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How is a scar formed?
macrophages stimulate fibroblasts to produce collagen
What is the funtion of IgA?
is secreted into GI & respiratory lumen where it binds to bad guys and takes care of them before they get out
What all happens with the antigen for a parastic worm?
- it is presented to a helper cell, which activates the B-cell
- B-cell diff into plasma cell, which produces IgE, which binds to a receptor on the mast cell
- Mast cell degranulates
What is released when mast cells degranulate by activation of a parasitic worm antigen?
- histamine (increases vasc permeability & allows eosinophils to move out of BV)
- eosinophil chemotactic factor (moves eosinophils twd worm; the receptor on eosinophil sees the IgG ab on the worm, degranulates, and tries to kill the worm)
Immune privilege sites (T-cells are not allowed to enter).
- Placenta or Fetus
- Testes or Ovaries
- Eyes & Brain