Diseases with fever and rash

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  1. Centrally distributed maculopapular rash
    • Acute meningococcemia
    • Drug induced hypersensitivity syndrome/Drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS)
  2. Discrete maculopapular lesions that become confluent, spreads from hairline downward sparing palms and soles lastingā‰„3 days. Associated symptoms: cough, conjunctivitis, coryza, severe prostration.
    Rubeola (measles (first disease)) *Preceded by Koplik's spots
  3. 1-2 mm white-to-bluish lesions with erythematous halo on buccal mucosa. Generally seen during the first 2 days of sx.
    Koplik's spots
  4. Discrete maculopapular rash that spreads from hairline downward, clearing as it spreads. May be accompanied by palatal petechiae. Associated symptoms: adenopathy, arthritis.
    Rubella (German measles (third disease))
  5. Palatal petechiae
    Forchheimer spots (may be found with rubella, infectious mono, and scarlet fever)
  6. Bright red "slapped-cheeks" appearance followed by lacy reticular rash that waxes and wanes over 3 weeks. Rarely, papular-purpuric "gloves-and-socks" syndrome. Associated symptoms: mild fever, arthritis in adults, rash following resolution of fever. Most common in children 3-12.
    Erythema infectiosum (fifth disease)
  7. Diffuse maculopapular rash over trunk and neck, resolves within 2 days. Associated symptoms: Rash following resolution of fever, usually affects children <3 years old
    Exanthem subitum (roseola (sixth disease))
  8. Nonspecific diffuse macules and papules; less commonly, urticarial or vesicular oral or genital ulcers.
    Primary HIV infection
  9. Diffuse maculopapular rash; urticaria, petechiae in some; periorbital edema (50%); palatal petechiae (25%). Associated symptoms: Hepatosplenomegaly, pharyngitis, cervical lymphadenopathy, atypical lymphocytosis.
    Infectious mononucleosis (Epstein-Barr virus). Rash occurs in 5% of cases, 90% if ampicillin is given.
  10. Intensely pruritic, bright-red macules and papules, symmetric on trunk and extremities; may become confluent. Associated symptoms: variable: fever, eosinophilia
    Exanthematous drug-induced eruption. Usually occurs 2-3 days after exposure in previously sensitized individuals, otherwise after 2-3 weeks (even after drug is discontinued).
  11. Maculopapular eruption appearing in axillae, spreading to trunk and later to extremities; usually spares face, palms & soles; evolves from blanchable macules to confluent eruption with petechiae. Associated symptoms: headache, myalgias.
    Epidemic typhus (vector: body lice) *10-40% mortality if untreated. Similar rash, but evanescent in recrudescent typhus.
  12. Maculopapular eruption usually sparing palms and soles. Associated symptoms: headache, myalgias
    Endemic (murine) typhus (vector: rat or cat fleas)
  13. Eschar common at bite site; maculopapular (rarely vesicular and petechial) rash on proximal extremities spreading to trunk and face. Associated symptoms: headache, myalgias, regional adenopathy.
    Rickettsial spotted fevers (vector: ticks
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Diseases with fever and rash
2015-10-01 20:18:48

Description of rashes accompanied by fever and their causes
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