Zoonotic2- E. coli, Campy, Listeria

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Zoonotic2- E. coli, Campy, Listeria
2015-10-13 18:34:46
vetmed zoonotic2

vetmed zoonotic2
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  1. E. coli infections are a primary cause of _________ among ________, especially in developing countries.
    diarrhea; children
  2. Most E. coli infections are __________.
  3. Shiga-toxin producing E. coli (STEC) is the same as... (2)
    enterohemorrhagic E. coli, vero toxin-producing E. coli
  4. Shiga toxin-producing E. coli (STEC) is NOT the same as... (2)
    enterpathogenic E. coli, enterotoxigenic E. coli
  5. What is the most important serotype/serovar are STEC? How is it identified?
    O157:H7; identified by O (LPS) and H (flagella) antigens
  6. Describe clinical discease caused by STEC in humans. (4)
    bloody diarrhea, severe stomach cramps, vomiting, +/- fever
  7. What is a sequela to infection with STEC, and what is it characterized by?
    hemolytic uermic syndrome; kidney failure, anemia, low platelets
  8. What is the leading cause of acute renal failure in children?
    hemolyic uremic syndrome caused by STEC
  9. Describe the 4 steps of infection with STEC.
    • 1. ingestion
    • 2. colonization of lower GI
    • 3. attachment to intestinal epithelial cells
    • 4. host absorption of shiga toxin
  10. Symptoms associated with STEC are caused by the __________.
  11. Diagnosis of STEC is by culture on __________; E. coli is __________.
    sorbitol-MacConkey agar; sorbitol-negative
  12. Describe treatment of STEC in humans.
    Supportive therapy only; antibiotics are contraindicated b/c they cause increased release of toxin
  13. What is the only major reservoir of STEC?
    cattle- asymptomatic shedding ONLY
  14. What was the first organism to be considered adulterant?
    O157:H7 STEC (zero-tolerance policy)
  15. How is STEC spread? (5)
    contact with individuals with diarrhea,consumption of undercooked ground beef, contamination of produce, swimming in/drinking contaminated water, contact with shedding animals
  16. Pre-harvest control of STEC on cattle farms. (3)
    probitocs, vaccination, diet modification
  17. What are the goals of HACCP? (3)
    eliminate fecal contamination of carcasses, kill surface contamination, reduce microbial growth
  18. _________ is not a reliable indicator of food saftey; you MUST...
    Color; use a food thermometer
  19. Zoonotic pathogens on every farm. (4)
    salmonella, STEC, crypto, campy
  20. Describe the microbiological characteristics of Campylobacter spp. (3)
    microaerophilic, motile, gram negative
  21. Which species of campy are poultry a main reservoir for?
    Campylobacter jejuni
  22. What species of Campy accounts for the vast majority of human cases?
    Campylobacter jejuni
  23. What species of campy are swine a primary reservoir for?
    Campylobacter coli
  24. What is the incubation period for campy in humans?
    2-5 days
  25. Symptoms of campy infection in humans (4). Treatment (1).
    fever, diarrhea, abdominal pain, nausea; usually self-limiting
  26. What are rare complications in human with campy? (3)
    septicemia, ractive arthritis, Guillain-Barre syndrome (paralysis)
  27. What kind of disease does campy cause in animals.
    usually subclinical, rarely enteritis in young animals
  28. What are methods of zoonotic transmission of campy? (3)
    food borne** in poultry and unpasteurized milk, environmental, direct transmission from infected animals/humans
  29. Medication approved for use for the control of mortality associated with E. coli in chickens and mortality associated with E. coli and P. multocida in turkeys.
    Baytril- fluoroquinolone - enrofloxacin
  30. Increased resistance of campy in humans to fluoroquinolones coincided with...
    approval of Baytril for veterinary use
  31. Campy outbreaks are more common in states that allow ___________.
    sale of unpasteurized milk
  32. Prevention and control of campy. (3)
    cook meat thoroughly, avoid kitchen cross-contamination, avoid raw dairy products
  33. What are the microbiological characteristics of Listeria spp.? (4)
    gram positive, bacillus, beta hemolytic, survives/proliferates at 4°C
  34. What are symptoms if Listeria infection in humans? (5)
    fever, diarrhea, vomiting, abortion, meningitis
  35. What is the incubation period of Listeria in humans?
  36. What kind of disease does Listeria cause in animals? (3)
    encephalitis, abortions, septicemia (most animals are susceptible, but only a fraction become ill)
  37. How is Listeria transmitted? What time of year is it common in animals?
    foodborne; winter and early spring (poor silage)
  38. With Listeria, most food contamination orignates from...
    the processing environment, not directly from animals.
  39. How can you avoid infection with Listeria? (5)
    avoid unpasteurized milk, thoroughly heat deli products (RTEs), observe best by dates, avoid cross contamination in kitchen, feed safety on the farm (silage)
  40. With Listeria infection, there is __________ in high risk populations.
    high mortality