HIV Drug Therapy

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Author:
dxc358
ID:
309277
Filename:
HIV Drug Therapy
Updated:
2015-10-09 11:55:49
Tags:
HIV Drug Therapy
Folders:
HIV Drug Therapy
Description:
HIV Drug Therapy
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  1. Nucleoside analog reverse transcriptase inhibitors (NRTIs)
    • Zidovudine (retrovir)
    • Didanosine (ddI, videx)
    • Zalcitabine (ddc, HIVID)
    • Lamivudine (epivir)
    • Stavudine (zerit)
    • Abacavir (ziagen)
  2. Zidovudine (retrovir)-s/e:
    BMS, GI intolerance
  3. Didanosine (ddI, videx)-s/e:
    pancreatitis, peripheral neuropathies
  4. Zalcitabine (ddc, HIVID)-s/e:
    peripheral neuropathies, stomatitis
  5. Lamivudine (epivir)-s/e:
    minimal toxicity, lactic acidosis
  6. Stavudine (zerit)-s/e:
    peripheral neuropathy, lipodystrophy
  7. Abacavir (ziagen)-s/e:
    hypersensitivity reaction
  8. Non-nucleoside analog reverse transcriptase inhibitors
    • Nevirapine (viramune)
    • Delavirdine (rescriptor)
    • Efavirenz (sustiva)
  9. Nevirapine (viramune)-s/e:
    rash, hepatitis
  10. Delavirdine (rescriptor)- s/e
    rash, headache
  11. Efavirenz (sustiva)-s/e:
    rash, CNS symptoms (dizzy, confusion)
  12. Protease inhibitors
    • Ritonavir (norvir)                    
    • Indinavir (crixivan)                      
    • Nelfinavir (viracept)                    
    • Lopinavir (kaletra)
  13. Ritonavir (norvir)-s/e:
    GI intolerance, paresthesias
  14. Indinavir (crixivan)-s/e:
    nephrolithiasis, GI intolerance
  15. Nelfinavir (viracept)-s/e:
    diarrhea, hyperlipidemia
  16. Lopinavir (kaletra)-s/e:
    GI intolerance, hyperlipidemia
  17. Fusion inhibitors
    Enfuvirtide (T-20) (Fuzeon)-s/e: pneumonia, hypersensitivity reaction
  18. Ribonucleotide reductase inhibitors
    Hydroxyurea (hydrea)

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