Deepest layer of the epidermis, composed of a single row of cuboidal or columnar keratinocytes. Undergoes cell division to continually produce new keratinocytes.
Superficial to the stratum basale, mainly consists of numerous keratinocytes arranged in 8-10 layers. Produce coarser bundles of keratin in intermediate flaments than those of the basal layer
Middle of epidermis, consists of three to five layers of flattened keratinocytes that are undergoing apoptisis. The nuclei and other organelles of these cells begin to degenerate as they move farther from their source of nutrition.
Present only in the thick skin of ares such as fingertips, palms, and soles. Consist of four to six layers of flattened clear dead keratinocytes. Provides an additional level of toughness in this region of thick skin
Consist on average of 25 to 30 layers of flattened dead keratinocytes. Cells are extremely thin, flat, plasma membrane. Final product of the differentiation process of the keratinocytes.