Pharmacology Dr. Brown Ch 12 Antiparasitics

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Pharmacology Dr. Brown Ch 12 Antiparasitics
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2016-11-10 17:49:53
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Antiparasitics
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Antiparasitics Dr Brown
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  1. Ideal characteristics of antiparasitics
    • Selective toxicity
    • Doesnt induce resistance¬†
    • Economical
    • Environmentally friendly
    • Easy to apply
  2. Dog breed sensitive to Ivermectins
    Collies
  3. Inhibitory neurotransmitter involved with the effects of diazepam tranquilizers
    GABA
  4. Tapeworm segments
    Proglottids
  5. Type of cholinergic receptors that when stimulated produce muscle tremors and eventually paralysis
    Nicotinic receptors
  6. Compounds that specifically inhibit coccidia protozoa
    Coccidiostats
  7. Means dilated pupils
    Mydriasis
  8. Term used to describe compounds that kill flukes
    Antitrematodal
  9. Condition that occurs after recovery from acute organophosphate toxicosis
    Delayed neurotoxicity
  10. Cholinergic receptor that when stimulated produce SLUDDE signs of organophosphate toxicosis
    Muscarinic receptors
  11. Anthelmintics that kill both internal and external parasites
    Endectocides
  12. Neurotransmitter associated with parasympathetic effects
    Acetylcholine
  13. General term used to describe compounds that kill a wide range of internal parasites
    Anthelmintic
  14. Molecule responsible for moving drugs like ivermectin from the CNS into the blood; part of the blood-brain barrier functional mechanism
    P-glycoprotein
  15. Term used to describe compounds that kill worms that are round in cross-section
    Antinematodal
  16. Inhibitory neurotransmitter thought now to account for the effects of ivermectin
    Glutamate
  17. Refers to something that floats along in the blood vessel until it lodges and causes obstruction
    Emboli
  18. Type of drug that kills heartworm adult worms
    Adulticide
  19. Term used to describe compounds that kill protozoa
    Antiprotozoal
  20. Parasites that live on the outside of the animals body
    Ectoparasites
  21. Means coughing up blood
    Hemoptysis
  22. Means kills parasite egss
    Ovicidal
  23. Enzyme that destroys acetylcholine to terminate its action
    Acetlycholinesterase
  24. Means itching
    Pruritus
  25. Term used to describe compounds that kill tapeworms
    Anticestodal, cestocides or taeniacides
  26. Compounds that kill young produced by adult heartworms
    Microfilaricide
  27. Means that an insecticide is much more poisonous to the parasite than it is to the host animals
    Selective toxicity
  28. Advantage active ingredient
    Imidacloprid
  29. Program active ingredient
    Lufenuron
  30. Immiticide active ingredient
    Melarsomine
  31. Revolution active ingredient
    Selamectin
  32. Interceptor active ingredient
    Milbemycin oxime
  33. Heartgard active ingredient
    Ivermectin
  34. Sentinel active ingredient
    Milbemycin oxime plus lufenuron
  35. Panacur active ingredient
    Fenbendazole
  36. Strongid, Nemex active ingredient
    Pyrantel
  37. Droncit active ingredient
    Praziquantel
  38. Frontline, Top Spot active ingredient
    Fipronil
  39. Capstar active ingredient
    Nitenpyram
  40. One of the safest groups of external insecticides characterizied by its quick knock down made from chrysanthemum
    Pyrethrins
  41. Group of internal and external antiparasitic drugs that works primarily by stimulation of the inhibitory neurotransmitter glutamate receptors
    Macrolides (avermectins and milbemycins)
  42. Originally developed for demodicosis, toxic if ingested. a2 agonist.
    Amitraz
  43. Toxicosis from endectocide results in CNS depression and is exhibited by ataxia, depression, blindness, and coma
    Ivermectin
  44. Safe roundworm medication found in grocery store, OTC, vermifuge.
    Piperazine
  45. Topically administered endectocide, controls fleas and ticks, ear mites, sarcoptic mange, avermectin-type drug
    Selamectin
  46. Antiprotozoal used in calves and avian species, causes thiamin deficiency
    Amprolium
  47. Arsenical adulticide against Dirofilaria, requires deep IM injection
    Melarsomine
  48. Drugs blocked from getting to the brain by P-glycoprotein
    Macrolides
  49. Group of insecticides that works by blocking acetylcholinesterase
    Organophosphates and carbamates
  50. Milbemycin type of antiparasitic approved for cattle and horses, active ingredient in Proheart 6
    Moxidectin
  51. Prototype drug for benzimidazoles
    Thiabendazole
  52. Antiprotozoal drug developed to be effective against agent that causes EPM
    Ponazuril
  53. Microfilaricide most commonly used
    Ivermectin
  54. Benzimidazole approved for use in dogs horses and livestock, trade name Safe-guard
    Febendazole
  55. Antinematodal pleasant tasting liquid suspension given PO
    Pyrantel
  56. Toxic signs include SLUDDE or muscle tremors progressing to paralysis
    Organophosphate
  57. Single-treatment tapeworm medication
    Praziquantel
  58. HW preventative avermectin approved for use in cats and dogs once a month, first canine HW preventative
    Ivermectin
  59. Oral macrolide HW preventative but not an avermectin
    Milbemycin oxime
  60. Topically applied flea insecticide, blocks nicotinic receptors
    Imidacloprid
  61. Flea tablet, inhibits chitin formation in larave and egg
    Lufenuron
  62. Daily administered oral HW preventative medication
    Diethylcarbamazine (DEC)
  63. Macrolide HW preventative used in dogs and cats that is similar in structure as avermectins, treats ear mites in cats
    Milbemycin
  64. Antibacterial drug that is also antiprotozoal, has neurological effects at high doses
    Metronidazole
  65. Injectable and pour on avermectin type drug approved for use in cows and pigs
    Doramectin
  66. Insecticides associated with SLUDDE signs
    Organophosphate and carbamates
  67. Added to pyrethrins to increase their killing activity, synergist drug
    Piperonyl butoxide
  68. Topically applied insecticide removes inhibitory effect of GABA on the nervous system
    Fipronil
  69. Antidote for organophosphate or carbamate toxicosis
    Atropine
  70. Oral tablet flea adulticide, rapid death of fleas, nicotine type compound stimulates muscle movement and paralyzes the fleas
    Nitenpyram
  71. JHM for fleas, larvae dont mature to adults
    Pyriproxyfen
  72. Insect repellent often used in human repellent products, can cause neurologic side effects
    DEET (Diethyltoluamide)

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