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PHRD7095 PTX7 Lecture 12 - Molecular Targets in Cancer (doses & t1/2 ONLY)

Home Get App Take Quiz Create tamoxifen dosing 20mg po QD tamoxifen t1/2 7-14 days anastrozole dosing 1mg po qd anastrozole t1/2 2 days letrozole dosing 2.5mg po qd letrozole t1/2 2 days exemestane dosing 25mg po qd exemestane t1/2 1 day traztuzumab dosing LD: 4mg/kg IV over 90min MD: 2mg/kg IV weekly OR 6mg/kg IV q3wk traztuzumab t1/2 6 (2mg/kg MD)or 16 days (6mg/kg MD) bicalutamide dosing 50mg po qd bicalutamide t1/2 7 days enzalutamide dosing 160mg po qd enzalutamide t1/2 6-8 days abiraterone dosing 1000mg po qd + prednisone 5mg BID abiraterone t1/2 12 hours bevacizumab dosing (colon & lung) colon: 5, 7.5, or 10mg/kg lung: 15mg/kg IV over 90min on an every 2-3week sched bevacizumab t1/2 20 days cetuximab dosing LD: 400mg/m2 IV over 90min MD: 250mg/m2 IV weekly BSA equation cetixumab t1/2 5 days erlotinib dosing 150mg po qd erlotinib t1/2 1-1.5 days afatinib dosing 40mg po qd afatinib t1/2 37 hours crizotinib dosing 250mg po bid crizotinib t1/2 42 hours ceritinib dosing 750mg po qd ceritinib t1/2 42 hours vemurafenib dosing 960mg po bid vemurafenib t1/2 57 hours dabrafenib dosing 150mg po bid dabrafenib t1/2 parent: 8 hrs active metab: 10 & 21 hrs trametinib dosing 2mg po qd trametinib t1/2 4-5 days ipilimumab dosing 3mg/kg over 90min q3wks (4 total doses) ipilimumab t1/2 15 days pembrolizumab dosing 2mg/kg IV over 30min q3wks pembrolizumab t1/2 26 days nivolimumab dosing 3mg/kg over 60min q2wks nivolimumab t1/2 26 days

Author daynuhmay ID 310131 Card Set PHRD7095 PTX7 Lecture 12 - Molecular Targets in Cancer (doses & t1/2 ONLY) Description cancer Updated 2015-10-23T07:45:38Z Show Answers