PHRD7095 PTX7 Lecture 12 - Molecular Targets in Cancer (doses & t1/2 ONLY)

Card Set Information

Author:
daynuhmay
ID:
310131
Filename:
PHRD7095 PTX7 Lecture 12 - Molecular Targets in Cancer (doses & t1/2 ONLY)
Updated:
2015-10-23 03:45:38
Tags:
cancer
Folders:

Description:
cancer
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user daynuhmay on FreezingBlue Flashcards. What would you like to do?


  1. tamoxifen dosing
    20mg po QD
  2. tamoxifen t1/2
    7-14 days
  3. anastrozole dosing
    1mg po qd
  4. anastrozole t1/2
    2 days
  5. letrozole dosing
    2.5mg po qd
  6. letrozole t1/2
    2 days
  7. exemestane dosing
    25mg po qd
  8. exemestane t1/2
    1 day
  9. traztuzumab dosing
    • LD: 4mg/kg IV over 90min
    • MD: 2mg/kg IV weekly OR 6mg/kg IV q3wk
  10. traztuzumab t1/2
    6 (2mg/kg MD)or 16 days (6mg/kg MD)
  11. bicalutamide dosing
    50mg po qd
  12. bicalutamide t1/2
    7 days
  13. enzalutamide dosing
    160mg po qd
  14. enzalutamide t1/2
    6-8 days
  15. abiraterone dosing
    • 1000mg po qd
    • + prednisone 5mg BID
  16. abiraterone t1/2
    12 hours
  17. bevacizumab dosing (colon & lung)
    • colon: 5, 7.5, or 10mg/kg
    • lung: 15mg/kg
    • IV over 90min on an every 2-3week sched
  18. bevacizumab t1/2
    20 days
  19. cetuximab dosing
    • LD: 400mg/m2 IV over 90min
    • MD: 250mg/m2 IV weekly
  20. BSA equation
  21. cetixumab t1/2
    5 days
  22. erlotinib dosing
    150mg po qd
  23. erlotinib t1/2
    1-1.5 days
  24. afatinib dosing
    40mg po qd
  25. afatinib t1/2
    37 hours
  26. crizotinib dosing
    250mg po bid
  27. crizotinib t1/2
    42 hours
  28. ceritinib dosing
    750mg po qd
  29. ceritinib t1/2
    42 hours
  30. vemurafenib dosing
    960mg po bid
  31. vemurafenib t1/2
    57 hours
  32. dabrafenib dosing
    150mg po bid
  33. dabrafenib t1/2
    • parent: 8 hrs
    • active metab: 10 & 21 hrs
  34. trametinib dosing
    2mg po qd
  35. trametinib t1/2
    4-5 days
  36. ipilimumab dosing
    3mg/kg over 90min q3wks (4 total doses)
  37. ipilimumab t1/2
    15 days
  38. pembrolizumab dosing
    2mg/kg IV over 30min q3wks
  39. pembrolizumab t1/2
    26 days
  40. nivolimumab dosing
    3mg/kg over 60min q2wks
  41. nivolimumab t1/2
    26 days

What would you like to do?

Home > Flashcards > Print Preview