Pharmacology Ch 9 Dr Brown Behavior Pharmacotherapy

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  1. General term for a group of drugs that decrease the incidence or controls the onset of convulsions
  2. Seizures that manifest themselves as spastic movement caused by stimulation of motor nerves in the brain or spinal cord
  3. Recurrent seizure activity
  4. Measurement of mass of some drugs
  5. Recurrent seizure activity of unknown origin
    Idiopathic epilepsy
  6. State of being in a seizure or term used to describe the condition of an animal having prolonged seizure activity
    Status epilepticus
  7. Liver disease caused by a drug
    Drug induced hepatopathy
  8. Partial or generalized seizure
  9. Means increased drinking
  10. Seizure that involves only localized muscle movement
    Partial seizure
  11. Term meaning metabolism of the drug has been sped up
  12. Means increased appetite
  13. Seizure that produces convulsions that involve the whole body
    Generalized seizures
  14. Behavior changes that occur before the actual seizure
    Preictal phase or aura
  15. Part of the brain associated with controlling and generating emotions
    Limbic system
  16. Mood-elevating drugs that include MOAIs, SSRIs, and TCAs
  17. Group of drugs that decreases fear responses
  18. Inhibitory neurotransmitter associated with the mechanism of action for diazepam and other benzodiazepine tranquilizer
    Y-aminobutyric acid
  19. Drug most commonly used and administered by the client for maintaining long-term control of seizure activity
  20. Drugs that work by blocking the removal of the serotonin neurotransmitter from the synapse
    Selective serotonin reuptake inhibitor
  21. Drug most commonly added to phenobarbital to enhance long-term control over persistent seizure activity
    Potassium bromide
  22. Approved for use in dogs to control seizures; primary metabolite is phenobarbital; implicated in drug-induced hepatopathy
  23. Drug most commonly used for IV infusion control of status epileptics
  24. Antipsychotic drugs that act by blocking dopamine stimulation of the limbic system
    Phenothiazine tranquilizer
  25. Approved vet drug used to treat generalized anxiety and separation anxiety in dogs and cats, approved for obsessive compulsive disorders in dogs
  26. Human anticonvulsant that is poorly absorbed and rapidly metabolized by dogs
  27. Vet approved drug for use in treating Cushings disease and canine cognitive dysfunction
    Selegiline (deprenyl)
  28. TRUE OR FALSE. After a few weeks on phenobarbital to control seizures, the dose typically needs to be decreased to compensate for side effects that occur
  29. TRUE OR FALSE. Cats typically require a lower dose of phenobarbital than dogs do
  30. TRUE OF FALSE. Signs of polyuria and polydipsa in a dog on phenobarbital usually indicate serious kidney disease
  31. TRUE OR FALSE. Preferred route for administration of diazepam in the dog is by mouth
  32. TRUE OR FALSE. Potassium bromide has an advantage as an anticonvulsant because it reaches equilibrium in the body after only 2 or 3 doses
  33. TRUE OR FALSE. Phenothiazine tranquilizer drugs may cause inappropriate aggressive behaviors of animals to emerge
  34. TRUE OR FALSE. TCAs have an advantage over phenothiazines such as acepromazine because they do no suppress overall behavior as much as phenothiazines do
  35. TRUE OR FALSE. Increases presence of dopamine neurotransmitter has been associated with a senility-like syndrome in dogs
  36. TRUE OR FALSE. Diazepam reduces anxiety by decreasing amount of GABA
  37. TRUE OR FALSE. There is no simple magic bullet for behavior therapy
  38. Periods of altered brain activity characterized by loss of consciousness, increased muscle tone or movement, altered sensations, and other neurologic changes
  39. Seizure with no convulsions, more like a state of semiconsciousness
    Absence seizure
  40. After the seizure activity has subsided. Patient seems tired, confused, anxious, and blind.
    Postictal phase
  41. Phenobarbital
    Use, how it works, contraindications, side effects
    • Use: Anticonvulsant, anesthetic 
    • How it works: Decreases and stabilizes neuron activity
    • Cons: CNS depressants, corticosteroids 
    • Side effects: Lethargy, sedation, anemia
  42. Diazepam
    Use, how it works, contraindications, side effects
    • Use: Anticonvulsant, tranquilizer 
    • How it works: Promotes GABA in the brain 
    • Cons: CNS depressants 
    • Side effects: Lethargy, aggression, excitement
  43. Potassium bromide
    Use, how it works, contraindications, side effects
    • Use: Anticonvulsant
    • How it works: Decreasing seizure activity in the CNS 
    • Cons: Kidney dysfunction, pregnancy 
    • Side effects: Sedation, vomiting
  44. Levetiracetam 
    Use, contraindications, side effects
    • Use: Anticonvulsant
    • Cons: Kidney disease 
    • Side effects: Loss of appetite, drowsiness
  45. Zonisamide
    Use, how it works, contraindications, side effects
    • Use: Anticonvulsant
    • How it works: Blocks sodium and calcium channels
    • Cons: Pregnant, sensitive to sulfa drugs 
    • Side effects: Sedation, ataxia
  46. Acepromazine
    Use, how it works, contraindications, side effects
    • Use: Antipsychotic, tranquilizer 
    • How it works: Act on dopamine receptors
    • Cons: Liver/kidney/heart disease 
    • Side effects: Increased seizures, hypotension
  47. Amitriptyline 
    Use, how it works, contraindications, side effects
    • Use: Antidepressant (TCA)
    • How it works: Prevents reabsorption of serotonin and and norepinephrine 
    • Cons: Diabetes, kidney disease 
    • Side effects: Drowsiness, dry mouth, dry eyes
  48. Clomipramine
    Use, contraindications, side effects
    • Use: Antidepressant (TCA)
    • Cons: Seizures, liver/kidney disease 
    • Side effects: Lethargy, vomiting, diarrhea
  49. Fluoxetine
    Use, how it works, contraindications, side effects
    • Use: Antidepressant (SSRI)
    • How it works: Increases serotonin levels in the CNS
    • Cons: Diabetes, seizures 
    • Side effects: Sedation, anorexia
  50. Selegiline
    Use, how it works, contraindications, side effects
    • Use: Antidepressant (MAOI), cushings disease 
    • How it works: Increase dopamine in brain 
    • Cons: Pregnant 
    • Side effects: Vomiting, diarrhea, lethargy
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Pharmacology Ch 9 Dr Brown Behavior Pharmacotherapy
2016-10-23 19:18:02
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Pharmacology Ch 9 Behavior Pharmacotherapy
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