Zoonotic3- Rodents

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Zoonotic3- Rodents
2015-10-28 20:19:04
vetmed zoonotic3

vetmed zoonotic3
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  1. Describe Hantavirus disease in humans.
    bilateral interstitial pulmonary infiltrates and respiratory compromise
  2. Reservoir for Hantavirus.
    rodents (deer mice-Peromyscus)
  3. What kind of virus is Hantavirus (Sin Nombre virus)?
    ssRNA virus
  4. Describe the prodromal (initial) stage of Hantevirus infection in humans. (5)
    fever, chills, myalgia, headache, GI symptoms
  5. Describe the pulmonary signs of Hantavirus in humans. (4)
    tachypnea, tachycardia, hypotension, crackles or rales on lung auscultation [may eventually need assisted ventilation]
  6. Describe transmission of Hantavirus b/w mice. (5)
    chronically-infected rodent--> horizontal transmission by aggressive behavior b/w mice, aerosols, contact with mucous membranes, skin breaches, urine
  7. What are routes of human infection with Hantavirus. (3)
    inhalation of aerosolized saliva and urine, dried excreta contact with broken skin/mucous membranes, rodent bites
  8. Risk factors for contraction of Hantavirus. (3)
    rodent in household, cleaning (other activities that aerosolize dust), certain occupations (grain farmers, livestock herdsmen, etc)
  9. ___________ infection is not considered a risk factor for Hantavirus.
  10. Describe prevention of Hantavirus infection. (2)
    control mice inside and outside, use PPE (gloves, masks) when cleaning
  11. The etiologic agent of monkeypox is a ____________ that was first discovered in ___________.
    orthopoxvirus; African monkeys
  12. Is monkeypox easily transmitted from human to human?
  13. What is the reservoir for monkeypox in endemic areas?
    native squirrels
  14. Describe infections with monkeypox virus in humans. (5)
    fatigue, fever, muscle pain, progressing to vesicles and pustules that scab in about 10 days, lymphadenopathy
  15. Clinical signs of monkeypox virus in rabbits and rodents. (9)
    conjunctivitis, nasal d/c, fever, cough, lymphadenopathy, lethargy, anorexia, progressing to nodular rash and pneumonia
  16. Clinical signs of monkeypox in monkeys. (2)
    pus-filled papules on hands/trunk/tail, ulcers in mouth
  17. Monkeypox was transmitted to an american family,veterinarian, and a rabbit at the vets office by a(n) ___________.
    prairie dog
  18. How the the FDA-CDC act to prevent/control monkeypox in the US?
    banning the importation and sale of African rodents and prairie dogs
  19. How long should you quarantine animals that came in contact with monkeypox? How long should people exposed to monkeypox be alert for signs and symptoms?
    30 days for both
  20. What species are persistently infected with lymphocytic choriomeningitis virus?
    mice and hamsters
  21. Lymphocytic choriomeningitis virus causes what 3 syndromes?
    aseptic meningitis, encephalitis, or meningoencephalitis
  22. What rodent-transmitte disease is VERY dangerous during pregnancy, and what does it cause in the fetus?
    lymphocytic choriomeningitis virus; congenital hydrocephalus, chorioretinitis, and mental retardation
  23. What is the primary host and natural host of lymphocytic choriomeningitis virus?
    house mice- Mus musculus
  24. Where is lymphocytic choriomeningitis virus found in mice?
    saliva, urine, feces
  25. What disease does LCMV cause in rodents?
  26. How do humans contract LCMV? (5)
    fresh urine, fecal droppings, saliva, contaminated nesting materials; contact of these substances with broken skin or conjunctiva; ALSO vertical transmission from mother to fetus
  27. Describe prevention of LCMV. (4)
    rodent control, ventilate rooms that may be contaminated before cleaning, clean with bleach, wear PPE when cleaning