Serum protein con of 5.2g/dL is equivalent to __________ IgG/dL.
For healthy seeming calves, normal serum TP is _________; for moribund calves, normal serum TP is __________. [to be considered adequate passive transfer of immunity]
5.2g/dL; 5.5g/dL (due to hemoconc)
Describe the sodium sulfite turbidity test for FPTI.
18% sodium sulfite--> becomes turbid= at least 1000 mg/dL IgG
Describe the lateral flow ELISA test for FPTI.
pass or fail for adequate IgG (as good as TP or sodium sulfite)
Why can serum GGT be used to evaluate for FPTI?
calves that have ingested colostrum will have high GGT compared to adult cows
Calves at _________ [age] with serum GGT _________ should be considered to have FPTI.
<2 weeks; 50IU/L
Describe treatment of FPTI.
feed calves, keep warm, low stocking density, plasma or whole (problem: prob doesn't need RBCs, and can only give a certain volume before you overload) blood transfusion
Describe the pathogenesis of secretory diarrhea.
ingestion of pathogen--> secrete enterotoxins that alter cellular cAMP--> increased secretion of Na+, K+, Cl-, bicarb--> water follows--> high volume diarrhea, acidosis, dehydration
What etiologic agents cause secretory diarrhea? (2)
enterotoxigenic E. coli, some Salmonella
Describe the pathogenesis of malabsorptive diarrhea.
inflammatory destruction--> increased hydraulic pressure in wall--> increse prostaglandin production--> descruction of absorptive surfaces--> malabsorption and fermentation in large intestine--> osmotic diarrhea
Malabsorptive diarrhea is ________; pathogens that cause it include... (5)
osmotic; Protozoa, rotavirus, coronavirus, some Salmonella, Clostridium
Pathogens that cause protein-losing enteropathy. (2)
With scours, fluid loss if primarily from the _________ and can lead to __________.