BIO131 final HORMONES
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myogenic mechanism- what triggers it? what does it do?
triggered by high map. It causes the afferent arterioles to contract to decrease flow rate, lowering MAP and GFR
if the myogenic isn't enough, the macula densa senses salt and tells the afferent arteriole to constrict more
what does RAA do and where does it come from?
it decreases GFR to prevent H2O loss when MAP is lower than 80 mmHg
what does ANP do and where does it come from?
increases GFR to reduce fluid volume in the body when map is above 180 mmHg
why don't you want GFR to be too high
filtered substances might not be fully absorbed
why dont you want GFR to be too low
accumulation of waste products
Angiotensin 2 what does it do
increases surface area of the mesangial cells to relax the cell for more filtration
help help my BP is low, come and save me angio
difference in ascending and descending limb
descending limb only permeable to water
ascending limb only permeable to salt
Counter current multiplier
set up osmolarity gradient in the vasa recta that allows reabsorption of water in the collecting duct and descending limb.
what does renin do? where does it come from?
comes from the kidney, turns angiotensinosen into angiotensin 1 when blood flow to the kidney is low
activated when BP is low. causes constriction in blood vessels to create more resistance and raise blood pressure
regulates sodium and potassium(reabsorption of salts)
comes from RAA in adrenal cortex
reabsorbs water, posterior pituitary gland
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