CMI Cell-Mediated Immunity

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CMI Cell-Mediated Immunity involves what kinds of cells?
- T-cells (helper, killer, suppressor)
- Macrophages (antigen-presenting cells)
- Memory Cells ( circulates to remember)
What are the functions of Cell-mediated Immunity?
- Recognition of self from non-self
- Surveillance system
- Target Cells
- Response regulated by cytokines.
What are the functions of the Helper T-Cells?
- "help" the antigen-driven maturation of B and T cells
- Facilitate and magnify the interactions between Antigen Presenting Cells (APC's) and immunocompetent lymphocytes.
- recognizes self cells and non-self cells.
- secretes lymphokines that increase bone marrow production of stem cells and speed up T-cell maturation.
NK Cells:
- Natural Killer Cells:
- have cytotoxic effects n non self cells without first being sensitized.
Suppressor T-Cells

prevents hypersensitivity by secreting lymphokinines that suppresses immune system cells.
Cytokines
- protein horemones produced by WBC's
- they act like messengers and tell specific cells when to respond.