Derm1- Skin Bacteriology

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  1. What are some gram + resident microbiota (rarely associated with disease)? (5)
    coag-negative staph, Bacillus, Micrococcus, alpha and gamma hemolytic strep, Corynebacterium
  2. What are some gram - resident microbiota (rarely associated with disease)? (2)
    Acinetobacter, Pseudomonas (except P. aeruginosa)
  3. What are gram + transient microflora (significant only if associated with disease)? (2)
    Coag-positive staph, beta-hemolytic strep
  4. What are gram - transient microflora (significant only if associated with disease)? (2)
    Pseudomonas aeruginosa, coliform bacteria
  5. A practitioner takes a surface
    swab of this inflamed skin.
    Culture returns as:
    – S. pseudintermedius: moderate
    – Proteus mirabilis: light
    – β‐hemolytic Streptococcus sp.:
    light
    Which organisms are most
    likely significant?
    Staph pseudointermedius (b/c is is transient flora that can act as an opportunist) 

    [strep would be more worrisome if it was from a deep wound]
  6. What are important opportunistic pathogens associated with primary dermatologic disease (superficial)? (2)
    coag-positive staph (pseudointermedius), Pseudomonas aeruginosa
  7. What are important opportunistic pathogens associated with wounds (deep derm disease)? (4)
    coag-neg staph, Pseudomonas aeruginosa, coliform bacteria, beta hemolytic strep
  8. What are coag-postive staph species? (6)
    aureus, intermedius, pseudointermedius, delphini, lutrae, schleiferi ssp. coagulans
  9. What is different about dogs colonized with MRSA than people?
    dogs decolonize within 2-3 weeks if removed from environment with colonized person (people are colonized forever)
  10. What are the carriage sites for Staph pseudintermedius in healthy dogs? (4)
    nose, mouth, perineum-rectum, and groin
  11. Describe the unique characteristics of Pseudomonas aeruginosa? (4)
    intrinsic resistance to many antimicrobial drugs, adept opportunist, can cause green exudate, usually causes deep disease (but can cause superficial
  12. Rapidly progressive infection of subcutis and along fascial planes.
    necrotizing fasciitis
  13. What bacteria is necrotizing fasciitis associated with? (3)
    Staph pseudintermedius, beta-hemolytic strep, and very rarely anaerobes (Clostridium)
  14. ___________ play a key role in necrotizing fasciitis.
    Bacterial toxins
  15. What is the most common cause of NF in dogs?
    beta-hemolytic strep
  16. Beta- hemolytic strep can cause ____________, which leads to __(2)__.
    streptococcal toxic shock syndrome; hypotensive shock and multiorgan failure
  17. Why are fluroquinolones contraindicated in toxic shock syndrome?
    because they induce the lytic cycle in bacteriophage and release of toxins and enhancement of disease
  18. Definitive diagnosis of NF requires...
    clinical signs + histopathology + culture
  19. What is the "finger test"?
    when animal is sedated, incise first fascial plane, lack of bleeding and presence of "dishwater" fluid--> push down on fascia--> if it disintegrates with minimal pressure, very suggestive of NF
  20. Chronic deep pyogranulomatous bacterial infections can be caused by... (4)
    Actinomycese, Nocardia, rapidly growing Mycobacterium, Corynebacterium pseudotuberculosis
  21. What are the key features of Actinomyces? (3)
    normal oral microbiota, strict/facultative anaerobes, associated with non-healing wounds
  22. What are the key features of Nocardia? (4)
    ubiquitous in environment, obligate aerobes, associated with non-healing wounds, acid-fast staining
  23. Deep infections with Nocardia require what kind of treatment?
    extensive debridement
  24. Actinomyces is associated with __________, leading to ___________.
    migrating foreign bodies (splinters, grass awns); draining tracts
  25. In order to treat Actinomyces draining tracts, you must...
    follow the tract and remove the migrating foreign body.
  26. What are the key features of rapidly growing Mycobacterium? (4)
    ubiquitous in environment, non-contagious, obligate aerobes, acid fast
  27. Rapidly growing mycobacterium are _______ to cultivate in the lab; however,...
    easy; there are types of Mycobacterium that are "uncultivable"- "skin tuberculosis" of cattle, feline leprosy
  28. What is the etiologic agent of feline leprosy? What are characteristics of this disease?
    Mycobacterium lepraemurium- uncultivable mycobacterium- must be diagnosed by histopath with PCR- nodular lesions on extremities
  29. What is the etiologic agent of canine leproid granulomas? What are characteristics of this disease?
    uncultivable Mycobacterium- nodular ulcerated masses, esp on ears- spontaneously regress
  30. Ulcerative lymphangitis in horses is caused by _____________; characteristics of this disease include...
    Corynebcterium pseudotuberculosis; SHIT test (not very good), culture, caseous lymphadenitis

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Author:
Mawad
ID:
314464
Filename:
Derm1- Skin Bacteriology
Updated:
2016-01-22 15:40:19
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vetmed derm1
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vetmed derm1
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