Bio 3400 - Lecture 2 PII

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  1. Simple transporter structure
    12 transmembrane domains
  2. Peptidoglycan
    Rigid layer providing strength to cell wall
  3. Composition of peptidoglycan
    • Polysaccharide
    • N-acetylglucosamine or N-acetylmuramic acid
    • Amino acids
    • Lysine or diaminopimelic acid (DAP)
    • Different crosslinking in gram +,-
  4. Peptidoglycan linkage
    beta(1-4), Lysozyme sensitive
  5. Variations in peptidoglycan structure
    • Gram + : Peptide bridge
    • Gram + : Lysine
    • Gram - : DAP
  6. Peptidoglycan synthesis
    • 50nm wide cables
    • Crosslinking
    • Gram + has multiple layers
  7. Gram - (peptidoglycan)
    • 10% Peptidoglycan (cell wall)
    • Lipopolysaccharide replaces outer membrane phospholipids (toxic to animals)
  8. Aracheal peptidoglycan
    • No peptidoglycan - Pseudomerin instead (in some)
    • No outer membrane
  9. Pseudomurein
    N-acetylglucosamine and N-acetylsaminuronic acid

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Author:
Ant
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315266
Filename:
Bio 3400 - Lecture 2 PII
Updated:
2016-02-03 22:37:34
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Bio 3400
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Bio 3400
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