ADR- Bhave

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The flashcards below were created by user ebmalonzo on FreezingBlue Flashcards.


  1. β-lactam ADR
    • PCN
    • ● Hypersensitivity
    • ● Drug-induced hemolytic anemia
    • ● Superinfections
    • ● Convulsions
    • → High doses, renal failure, epileptic patients
    • Cephalosporin
    • ● Thrombophlebitis
    • ● Renal toxicity
    • ● Hypothrombinemia
    • Carbapenems
    • ● Seizures
    • → CNS disease, renal insufficiency
  2. Vancomycin ADR
    • ● Ototoxicity
    • ● Nephrotoxicity
    • ● “Red man” or “red neck” syndrome
  3. Aminoglycoside ADR
    • ● Ototoxicity
    • ● Nephrotoxicity
  4. Tetracycline ADR
    • ● GI
    • ● Photosensitivity
    • ● Hepatic toxicity
    • ● Renal toxicity
    • ● Teeth and/or bones
    • ● Allergy
    • ● Skin
    • ● Cross-sensitization
    • ● Thrombophlebitis
    • ● Minocycline: vestibular toxicity, ataxia
    • ● Long term use: leukocytosis, toxic granulation of granulocytes, and thrombocytopenic purpura
  5. Nitrofurantoin ADR
    • ● Anorexia
    • ● N/V
    • ● Rash/allergy
    • ● Neuropathies and hemolytic anemia occur in glucose-6-phosphate dehydrogenase deficiency
  6. Rifampicin ADR
    • ● Red-orange color to urine, sweat, tears, conacts
    • ● Rash
    • ● Thrombocytopenia
    • ● Nephritis
    • ● Cholestatic jaundice, hepatitis
    • ● Flu-like syndrome (fever, chills, anemia)
    • ● P450 inducer (increased elimination of cyclosporine, contraceptives, anticoagulants)
  7. Streptomycin ADR
    • ● Ototoxic
    • → CI: pregnancy
    • ● Nephrotoxic
    • ● Vertigo, hearing loss (permanent)
    • ● Adjust in renal insufficiency
    • ● Toxicity (age- elderly, use for <6 months)
  8. Cycloserine ADR
    • ● Peripheral neuropathy
    • ● CNS dysfunction (depression & psychotic reaction)
    • → CI: epileptic pts
  9. Isoniazid ADR
    • ● Peripheral neuropathy
    • ● Liver toxicity
    • ● Optic neuritis
    • ● Allergy
    • ● GI upset
    • ● Hemolytic anemia
    • ● P450 inhibitor (phenytoin toxicity)
    • ● CNS toxicity (memory loss, psychosis)
  10. Ethambutol ADR
    • ● Retrobulbar (optic) neuritis (loss of visual acuity and red-green color blindness)
    • → CI: children (cannot assess visual acuity)
    • ● GI upset
    • ● Hyperuricemia
    • ● Accumulates in renal failure (½ dose if CrCl < 10)

Card Set Information

Author:
ebmalonzo
ID:
316078
Filename:
ADR- Bhave
Updated:
2016-02-20 23:35:41
Tags:
ADR
Folders:
ID 1
Description:
ID 1 (Final): ADR (Bhave)
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