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When a generic drug and a brand name drug produce equivalent blood levels of pharmacologic substance, what are they said to be?
What does a Legend Drug require?
Which governmental agency is responsible for drug safety in the US?
The Controlled Substance Act is administered by which governmental agency?
DEA- Drug enforcement Administration
The medications record in the client chart prepared during the medical history review should include all of the following except?
A. DEA schedule category
B. Drug Name
C. Therapeutic use of the drug by the dental patient
D.Interactions with dental drugs
E. Side effects that could interfere with dental treatment
DEA Schedule category
Drugs are metabolized primarily in which organ?
Patent protection for the manufacture and marketing of a drug lasts for how many years?
Which characteristic of the drug molecule promotes receptor binding?
How does plasma protein binding affect drug effects?
Prevents passage of molecule through biological membrane
What is the most unpredictable route of administration?
The rate of absorption of a drug is related to all of the following except one:
a. amount of circulation to the area
b. concentration of the drug
c. affinity of the drug
d. wide area of absorptive surface
Affinity of the drug:
Affinity is important once the drug reaches the receptor site AFTER it is absorbed.
Which of the following is a parenteral route?
Sublingual medication is absorbed into the bloodstream, thus bypassing the GI Tract.
What is the safest route of administration?
Strongest Warning Required by the FDA
- Black Box Warning
- A black box warning means that medical studies indicate that the drug carries a significant risk of serious or even life-threatening adverse effects.
What factors can affect the rate of absorption from the GI Tract?
- 1. formulation of the drug (liquid or solid)
- 2. Concentration
- 3. Area of absorptive surface
- 4. How much drug is lost during first pass effect
- 5. Whether the patient has eaten or not
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