EENT-Derm plus pharm

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  1. nystatin (Mycostatin)
    Antifungal
    • Therapeutic class: antifungal
    • Preg cat: C
    • MOA: Binds to membrane sterols in fungal cell causing leakage-kill son contact
    • Indications: Topical fungal infections or oral fungal infections. depending on infection route may differ.
    • Contraindications: hypersensitivity
    • Adverse: skin irritation
  2. amphotericin (Fungizone)
    • Therapeutic class: Antifungal
    • Preg: B 
    • MOA: Binds to membrane sterols in fungal cell causing leakage-kills on contact
    • Indications: effective against a wide range of fungi
    • Contraindications: hypersensitivity 
    • Adverse: N/V, fever, chills, headache, nephrotoxicity
    • Alerts: Infuse slowly IV, hold for elevated BUN or creatinine.
    • Interactions: Many
  3. permethrin (Elimite, Nix)
    scabicide, pediculicide
    • Therapeutic class: Antiparasitic
    • Preg: B
    • MOA: Affects the nervous system of parasite causing paralysis, they did in 24-48 hours because they're unable to feed.
    • Indications: scabies, parasites
    • Contraindications: Hypersensitivity 
    • Adverse: itching, burning, rash, redness, edema
    • Alert: Caution with asthma, lactating or inflamed skin. Wear gloves-for lice-medications should remain on on head for 10 mins. Itching may persist for up to 2-3 weeks. Avoid Face and groin
    • 1% for Lice
    • 5% for scabies
  4. mafenide acetate (Sulfamylon)
    • Therapeutic class: antibacterial
    • Preg: C
    • MOA: Bacteriostatic: Interferes with bacterial cell-wall synthesis and metabolism– Effective against gram negative organisms
    • Indications: topical water soluble antibacterial agent in 2nd and 3rd degree burns.
    • Contraindications: hypersensitivity
    • Adverse: metabolic acidosis, respiratory alkalosis, blistering, superinfections. Life threatening reactions-Bone marrow suppression, fatal hemolytic anemia. 
    • Alert: Assess electrolytes and acid-base balance-BUN/creatinine
  5. Accutane
    • Therapeutic class: Antiacne
    • Preg: X
    • MOA: decreases sebum production, causes apoptosis in sebaceous glands as well as others. 
    • Indications: decrease sebum production, severe acne with cysts.
    • Contraindications: Pregnancy, sunburns, eczema, children under 12, hepatic disease, leukopenia, neutropenia
    • Adverse: Bone pain–, Fever, –Headache,– Nausea–, Vomiting, –Rash–, Stomatitis, –Pruritus–, Sweating –Ocular disorders 25% of patients develop retinoic acid syndrome (–Fever, Weakness, Fatigue, Edema, Pulmonary involvement)
    • Alert: occuations with prolonged sun exposure.
  6. Retinoid (Avita, Retin-A)
    • Therapeutic class: antiacne
    • Preg: C
    • MOA: Carboxylic acid form of vitamin A-for skin turnover.
    • Indications: Acne
    • Contraindications: 
    • Adverse: Increased sensitivity to sunlight, –Redness–, Scaling erythema, –Crusting and peeling of skin
  7. pilocarpine (Isoptocarpine)
    • Therapeutic class: parasympathomimetic 
    • Preg: C
    • MOA: muscarinic receptor agonist in PNS-causing contraction of iris sphincter muscles allowing an increase of aqueous outflow
    • Indications: open and closed angle glaucoma
    • Contraindications: narrow-angle glaucoma, hypersensitivity, pupillary block glaucoma, uncontrolled asthma,
    • Adverse: Dyspnea–, Hypertension–, Tachycardia–, Retinal detachment–, Bronchospasm [long term use]
    • Antidote: Atropine
    • Alert: Apply pressure to lacrimal ducts in order to prevent systemic effects.
  8. mydriasis causes what to the eyes?
    Dilation of pupils-cycloplegics-used for eye exams. not use for patient with glaucoma due to potential for glaucoma attack.
  9. Myosis is what condition of the eye?
    Constriction
  10. what is timoptic used for?
    • Is a non selective beta 1 and beta 2 adrenergic receptor blocking agent which reduces vasodilation.  decreases cardiac output and also causes a decrease in aqueous humor and an increase in outflow. 
    • Decreasing production of aqueous-decreasing intraocular pressure. used for open angle glaucoma, ocular hypertension, migraines, HTN. 
    • adverse effects: Bronchoconstriction( caution with asthma patients), dysrhythmias, hypotension, burning
    • Alert: remain immobile for 5 minutes before driving.
  11. what is xalatan used for?
    • believed to reduce intraocular pressure by increasing the outflow of aqueous humor.
    • dilates trabecular meshwork.Used for ocular hypertension and open angle glaucoma.
  12. Glaucoma
    • increased Intraocular pressure.
    • if left untreated leads to optic nerve damage
  13. auralgan anesthetic
    is an otic solution containing antipyrine, benzocaine, and dehydrated glycerin.
  14. Ottis media
    • inflammation behind the tympanic membrane-with accumulation of fluids. viral or bacterial
    • 48-72 hours is watchful waiting for children 2 years and older due to most being viral.
    • Can cause conductive hearing loss later in life.
  15. Long term use of prednisone can lead to?
    Cataracts.

Card Set Information

Author:
rmwartenberg
ID:
319981
Filename:
EENT-Derm plus pharm
Updated:
2016-06-27 04:25:24
Tags:
Nursing
Folders:
1st Year Nursing Pharm
Description:
open exam
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