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  1. Cyclosporine
    Immunosuppressant agent for organ transplants that comes in a liquid suspension used in tx of OLP in diabetic pts
  2. Mycostatin
    • example: Nystatin
    • -Topical antifungal
    • -Little side effects
    • -Use short term (high sugar content)
    • -oral suspension (can swallow) no sx effect
  3. Imidazoles
    • -example: clotrimazole, miconazole, keteoconazole (kete mostly used on skin, sx vers has a lot of side effects avoid)
    • -Topical antifungal
    • -MORE potent (use this for more severe cases)
  4. Amphotericin B
    • -IV and PO
    • -SEVERE systemic
    • -alternative to azoles
    • -side effect nephrotoxicity
    • -used for other fungal infection (aspergillosis)
  5. Fluconazole
    • -PO or IV antifungal
    • -systemic
    • -very potent
    • -under traizole category
  6. Itraconazole
    • -same as fluconazole
    • -oral suspension for topical and systemic effects
    • -under triazole category
    • -STRONG inhibitor of cytochrome P450 enzyme
  7. Glucocorticoid (list)
    • example: Prednisone, dexamethasone
    • -
  8. Immunophilin (list)
    • -example: cycosporine, tacrolimus, sirolimus
    • -organ transplant
    • -side effect: nephrotoxicity
  9. cyclosporine
    • -immunophilin
    • -oral solution
    • -eye drops
  10. cytotoxic drugs
    • used in cancer tx
    • causes BM suppression
    • examples: Azathioprine, mycophenolate, methotrexate
  11. Methotrexate
    • folic acid antagonist
    • used in rheumatoid arthritis
  12. Thalidomide
    good for behcets syndrome, apthous ulcers in HIV infections due to systemic problems
  13. Immune modulators (list)
    example: thalidomide, biological agents
  14. DMARDs
    • example: gold, sulfasalazine, dapsone
    • DMARDs are 3rd line therapy when all else failed
  15. Dapsone
    Abx used in tx of systemic RAS
  16. Anesthetic agents for tx of apthous ulcers
    • OTC benzocaine
    • Viscous lidocaine (only lasts 5 min)
    • compounded anesthetic (last 30 min-1hr)
  17. Amlexanox 5% paste
    • inhibits histamine release
    • limits duration of RAS
    • use this instead of CREST toothpaste
  18. List of topical steroids
    • Clobetasol
    • Fluocinonide
    • Betamethasone
  19. Betamethasone
    • topical steroid
    • intermediate strength
  20. Fluocinonide
    • topical steroid
    • POTENT
    • Most commonly used potent topical corticosteroid for tx of OLP
  21. Clobetasol
    • topical steroid
    • ULTRA potent
  22. Betamethasone
    • syrup form
    • intermediate potency
    • easy to access areas that cannot be applied topically
  23. Dexamethasone
    • high potency
    • elixer/also used as injection
    • Systemic agent that comes as liquid suspension, can be used both systemically and topically in tx of┬áMMP
  24. Prednisolone
    • syrup
    • ULTRA high potency
    • best used for systemic use
  25. Some corticosteroids are readily absorbed through ulcerated and inflamed surfaces. Those absorbed systemically can cause adrenal suppression if used more than _______. Continuous use reduces their effectiveness, withdrawal _________ restores action. Continuous use may lead to ___________ infections
    • 2 weeks
    • 2-4 days
    • candidal
  26. RAS + associated systemic conditions
    • Behcet
    • GI absorption problems (Crohns UC)
    • Cyclic neutropenia
  27. Systemic therapies in RAS
    • Prednisone
    • Thalidomide
    • Etanercept
    • Dapsone

Card Set Information

Author:
woaitzsuperman
ID:
320463
Filename:
OMED
Updated:
2016-05-25 04:48:32
Tags:
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Description:
omed
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