FNP2 Quiz 6 Hyperlipidemia

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  1. Secondary dyslipidemia causes.
    • DM
    • hypOthyroidism
    • obstructive liver disease
    • CRF
    • pharmaceuticals
  2. Screening for hyperlipidemia should begin at what age for kids with a positive fam h/o hyperlipidemia?
    2 yo
  3. All children, regardless of fam hx, should be routinely screened for hyperlipidemia at what ages?
    • between 9-11 and
    • 17-21 yrs
  4. Very high LDL, > ______ is often genetic. Very high triglycerides, > ______ are due to other diseases and meds
    • 190
    • 500
  5. For pts with polypharmacy or with major concerns about liver fun, which statins are a good choice?
    • prava-
    • flu-
    • or rosuvastatin
  6. _________statin is available free in some areas.
    atorva
  7. When are bile acid sequestrants CI?
    • elevated TG (esp > 400)
    • dysbetalipoproteinuria
  8. SE of bile acid sequestrants.
    • GI distress/constipation
    • decreased absorption of other meds
  9. What are some bile acid sequestrants?
    • cholestyramine
    • colestipol
    • colesevelam
  10. Major action of bile acid sequestrants.
    block cholesterol absorption
  11. How should you start a med of nicotinic acid?
    lower dose 1-2 x daily, EXR
  12. When should you advise a pt to take Niaspan nicotinic acid?
    with ASA or NSAID before bedtime to reduce temp flushing sensation
  13. When is nicotinic acid CI?
    • liver dz
    • severe gout
    • peptic ulcer
  14. SE of nicotinic acid.
    • flushing
    • hyperglycemia
    • hyperuricemia
    • upper GI distress
    • hepatotox
  15. Major axn of nicotinic acid.
    decreases production of TG and VLDL
  16. CI for fibrates.
    severe renal or liver dz
  17. SE of fibrates.
    • dyspepsia
    • gallstones
    • myopathy
    • increased risk of rhabdo w/ statins
  18. A benefit of _________ is that they reduce progression of coronary lesions.
    fibrates
  19. Fibrates are primarily used to _______.
    decrease TG
  20. _________ selectively absorb cholesterol from the small intestines.
    • cholesterol absorption inhibitors
    • Ezetimibe (Zetia)
  21. cholesterol absorption inhibitors like Ezetimibe (Zetia) are potentiated by ________ and ________.
    • fibrates
    • cyclosporine
  22. SE of cholesterol absorption inhibitors such as Ezetimibe (Zetia).
    • diarrhea, abd pain
    • increased LFTs
  23. ________ reduce LDL and apoB lipoprotein.
    • cholesterol absorption inhibitors
    • Ezetimibe (Zetia)
  24. __________ inhibit synthesis of VLDL in liver and lower TG 20-30%.
    omega 3s
  25. Who benefits from high dose statins?
    Individuals with known _________ or with LDL-C > ______.
    Age 40-75 who have ______ and LDL ___ - _____,
     or those with 10 year ASCVD risk > _____.
    • ASCVD
    • 190
    • DM, 70-189
    • 7.5
  26. High intensity statin therapy include statins that lower LDL-C by how much? What are specific examples?
    • > 50%
    • atorvostatin, rosuvostatin
  27. High intensity statin therapy should be initiated when?
    • DM with 10 year ASCVD risk 7.5% or higher
    • Anyone 40-75 yo with 7.5% or higher 10-yr risk of ASCVD (mod to high intensity statin)
    • LDL-C >  or = 190mg/dl (mod or high intensity statin)
  28. What are some things that negatively affect cholesterol?
    • steroids
    • progesterone
    • anti-psychotic meds
    • testosterone
  29. ATP guidelines state that _____ is a CHD risk equivalent.
    DM
  30. With DM, the 10-year risk for development of CHD increases how much?
    20%

Card Set Information

Author:
MeganM
ID:
321398
Filename:
FNP2 Quiz 6 Hyperlipidemia
Updated:
2016-06-27 17:01:10
Tags:
FNP2
Folders:
GU,FNP2,Exam 2
Description:
FNP2
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