Neurons & Nervous System part 3

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  1. a chemical synapse between motor neurons & skeletal muscle cells
    neuromuscular junction
  2. A motor neuron releases __ from its axon terminals.
    acetylcholine (ACh)
  3. The postsynaptic membrane of the muscle cell is the __
    motor end plate
  4. Voltages due to synaptic transmission & measured in the muscle are called __
    Endplate Potentials (EPPs)
  5. main neurotransmitters in the CNS
    • ACH: in skeletal muscles & CNS
    • Glutamate: an excitatory amino acid
    • Glycine & GABA: inhibitory amino acids
  6. Glutamate is __ and will result in __, but the __ of different receptors varies significantly
    excitatory; depolarization; timing
  7. __ receptors allow a rapid influx of Na+
    AMPA

    - an ionotropic glutamate receptor
  8. __ receptors first require a slight depolarization through other receptors & allow a slower Na+ influx, as well as Ca2+
    NMDA

    - an ionotropic glutamate receptor
  9. Neurotransmitters are cleared from the cleft after release in order to stop their action in several ways:
    • diffusion
    • reuptake by adjacent cells
    • Enzymes present in the cleft may destroy them.

    ex. Acetylcholinesterase acts on ACh.
  10. The postsynaptic cell must sum the __. Summation occurs at the __.
    excitatory & inhibitory input; axon hillock
  11. adds up messages at different synaptic sites
    spatial summation

    (details on page 899 in book)
  12. adds up potentials generated at the same site over time
    temporal summation

    (details on page 899 in book)
  13. Drugs treat the nervous system by modulating __
    synaptic interactions
  14. mimic or potentiate the effect of a neurotransmitter
    agonists
  15. block the actions of a neurotransmitter
    antagonists

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Neurons & Nervous System part 3
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2016-11-01 22:16:23
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