-
________ interacts with Coumadin and increases INR and risk of bleeding.
- Sulfa drugs
- Macrolides
- NSAIDs
-
A pt taking Lithium should have what checked in addition to blood levels of the drug?
TSH
-
There is an increased risk of rhabdo with statins and _______.
antifungals
-
When would you Rx HCTZ?
- uncomplicated HTN
- HF
- edema
- HTN + osteoporosis! (decreases Ca excretion)
-
AE of HCTZ.
- hyperglycemia
- hyperuricemia
- increased TG & LDL
- hypOkalemia
-
What should you give a pt in place of HCTZ if they are allergic to sulfa?
a K+ sparing diuretic - triamlerene or amiloride
-
________ drugs can cause or exacerbate CHF.
TZDs
-
When would you STOP Actos (a TZD)?
dyspnea, wt gain, cough
-
There is an increased risk of hyperkalemia with what type of pts and drugs with K+ sparing diuretics?
- renal dz
- DM
- elderly
- severly ill
- ACEIs and ARBs
-
AE of Lasix
- hypovolemia
- hypokalemia
- hyponatremia
- HTN
- Ototox
- Pancreatitis, Jaundice, rash
-
SE of BB.
- depression, fatigue (elderly)
- ED
- masks hypoglycemia (careful with DM)
- Rebound HTN with abrupt withdrawal
-
-
When should CCBs be avoided?
-
-
AE of CCB.
- HA
- peripheral edema
- HF
- increased QT
- ***constipation***
-
CCBs possibly interact with?
- macrolides except azith
- intraconazole
-
If pt has mono + strep and is allergic to PCN, what do you give?
macrolide
-
-
What to give if allergic to macrolides?
doxy or quin
-
Doxy is used to treat?
- chlamydial infections (cervicitis, PID, pna)
- atypical bacterial infections
-
Tetracycline used to treat?
- mod to severe acne (after 2-3 mos topical)
- rosacea
-
Careful/avoid what drugs in pts with MG?
-
Keflex is used to tx?
- cellulitis
- impetigo
- (ok in preg)
- *NOT MRSA*!!
-
AE of PCN
- diarrhea
- C.dif
- vaginitis (candida)
-
Avoid what with quinilones?
- amiodarone
- macrolides
- TCAs
- antipsychotics
- < 18 yo
- MG
- preg & BF
- *steroids
-
SE of quin
- dizziness
- HA
- insomnia
- mood changes
-
When do you avoid sulfonamides?
- G6PD anemia
- < 2 months old
- preg late 3rd trimester (kernicterus)
- Warfarin (increased INR)
-
Severe AE of sulfonamides.
SJS
-
When is it important to avoid NSAIDs?
- HF
- GI bleed
- severe renal dz
- Warfarin
- ASA
- ETOH
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