Major HIV Mutations

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The flashcards below were created by user Tarek on FreezingBlue Flashcards.


  1. M187V
    • Class: NRTI
    • Selected by:3TC/FTC and to a lower extent ABC and ddl
    • Resistance to: Lamivudine & Emtricitabine
    • +/- didanosine and Abacavir
    • Restores activity to: Zidovudine and Tenofovir

    Diminishes viral fitness by 50%!
  2. K65R
    • Class: nRTI
    • Resistance to: All nRTI 
    • Restores activity to:  Zidovudine (AZT)
  3. L74V
    • Class: nRTI
    • Resistance to: Abacavir (ABC) & Didanosine (DDI) 
    • Restores activity to: T& Zidovudine (AZT)
  4. TAMs
    • Class:nRTI
    • Resistance to: all nRTI
    • Restores activity to:
  5. Q151M complex
    • Class:nRTI (multinucleoside resistance)
    • Resistance to: Zidovudine AZT & Didanosine DDI
    • Activity preserved to: Tenofovir TDF
  6. Which mutations confer resistance to Tenofovir?
    • K65R
    • K70E
    • Other

Card Set Information

Author:
Tarek
ID:
331286
Filename:
Major HIV Mutations
Updated:
2017-10-16 05:44:52
Tags:
HIV mutations resistance
Folders:

Description:
Major HIV Resistance
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