Biochem

Card Set Information

Author:
sonny9141
ID:
33286
Filename:
Biochem
Updated:
2010-09-10 18:17:38
Tags:
Acid Base Disorder
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Description:
Acid/Base Disorder
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  1. Respiratory Acidosis: acute? compensated? Causes?
    • Acute: pH: 7.25 (~7.4), PCO2: 60mmHg (primary disturbance), HCO3-: 26mmol/L
    • Compensated: pH ~7.32, PCO2 is still high (can't fix), HCO3- is rising: 32mmol/L
    • Causes: Airway obstruction, Opioid drugs, anesthetics, Disease/injure to the phrenic n.; COPD, RDS, fibrosis of lung
  2. Respiratory Alkalosis: Acute, Compensated, Causes?
    • Acute: pH is >7.4, PCO2 <<40 (primary disturbance), HCO3- is remained ~22mmol/L
    • Compensated: pH ~7.42, PCO2 still low (can't fix), HCO3-: decreased <22mmol/L
    • Causes: Hyperventilation, Anxiety, fever, hypoxia (high altitude),
  3. Metabolic Acidosis: Acute, Compensated, Causes?
    • Acute: almost not observe b/c respiratory system will compensate quickly
    • Compensated: pH still <7.4, PCO2 is decreased (<35mmHg), HCO3- still low (primary disturbance)
    • Causes: high acid production: diabetic ketoacidosis, lactic acidosis, chronic renal failure
    • loss of HCO3-: Diarrhea, renal tubular acdosis (failure to secrete H+ and reabsorb HCO3-)
  4. Metabolic Alkalosis: Acute, Compensated, Causes?
    • Acute: not seen
    • Compensated: pH still high but close to normal (7.4),
    • PCO2: increased (>40mmHg)
    • [HCO3-]: remains high (primary disturbance)
    • Causes: Vomitting, pyloric stenosis, excessive consumption of antiacids, nasogastric suction

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