MCQ - Neurosurgery Brain tumors III
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Meningioma are derived from?
Meningomesothelial cells of arachnoidQ
Common site for Meningioma?
- Along the superior sagittal sinusQ
- • Most are slow growing and encapsulatedQ
Clinical features of meningioma?
- Motor deficit in 90% (spasticity and lower limb weakness)
- Sensory deficit in 60% or
- Sphincter dysfunction of bladderQ.
Radiological finding in meningioma?
- Enhance intenselyQ following contrast administration
- Abnormal vascular markingsQ
- Enlarged foramen spinosumQ on the side of lesion
- Dural tail
- Calcification in the tumorQ
Name intraaxial tumors?
• Neuronal • Astrocytoma (Glioma)Q • Lymphoma
Name extraaxial tumors?
• PitutaryQ • SchwannomaQ • MeningiomaQ
Derivative of craniopharyngioma?
Clinical features of craniopharyngioma?
- Hypopituitarism (90%)
- Diabetes insipidus (10%)
- Growth retardation (50%)Q
Treatment of craniopharyngioma?
- TranssphenoidalQ surgical resection followed by postoperative radiation
- Surgery alone is curative in less than half of patients because of recurrences due to adherence to vital structures or because of small tumor deposits in hypothalamus or brain parenchymaQ.
Which hormone should be replaced first in hypopituitarism in craniopharyngioma surgery?
MC cause of hyperpituitarism?
Pituitary adenomaQ, Pituitary adenomas arise primarily from the anterior pituitary glandQ•
How can Pituitary adenoma be differentiated from hyperplasia?
- Reticulin stainQ•
- Absence of reticulin stain in pituitary adenomaQ
Treatment of pituitary adenoma?
- Dopamine agonist, bromocriptineQ, can shrink prolactinomas
- OctreotideQ can reduce GH levels
Surgical approach of choice in pituitary adenoma?
Sublabial or intranasal trans-sphenoidalQ approach
MC suprasellar mass in children?
MC suprasellar mass in adults?
What is Cushing disease?
Pituitary dependent cause of Cushing syndrome (pituitary adenoma secreting excessive ACTH)
• MC spinal tumor?
• MC primary spinal tumor?
Nerve sheath tumorQ
MC intramedullary tumor?
MC site of primary spinal tumor?
Risk factors for CNS lymphoma?
- AIDS patients
- Transplant recipientsQ.
Why is CNS lymphoma also called as ghost-cell tumor?
Its tendency for partial to complete resolution on CT after the administration of steroidsQ. Glucocorticoids should be withheld before biopsy due to cytolytic effect on lymphoma cells leading to nondiagnostic tissue.
Treatment of CNS Lymphoma?
MC site of origin of acoustic neuroma?
Schwann cells superior vestibular nerve >Inferior vestibular (rarely cochlear)Q
Investigation for acoustic neuroma?
MRI with gadolinium contrast Q
Who discovered MRI?
LauterbeurQ in 1973
What is Nelson syndrome?
Spectrum of symptoms and signs arising from an adrenocorticotropin (ACTH)–secreting pituitary macroadenoma after a therapeutic bilateral adrenalectomy.
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