MCQ - Neurosurgery Brain tumors III

Meningomesothelial cells of arachnoidQ

• Along the superior sagittal sinusQ
• • Most are slow growing and encapsulatedQ

• Motor deficit in 90% (spasticity and lower limb weakness)
• Sensory deficit in 60% or
• Sphincter dysfunction of bladderQ.

• Enhance intenselyQ following contrast administration
• Abnormal vascular markingsQ
• Enlarged foramen spinosumQ on the side of lesion
• Dural tail
• Calcification in the tumorQ

• Neuronal • Astrocytoma (Glioma)Q • Lymphoma

• PitutaryQ • SchwannomaQ • MeningiomaQ

Rathke’s pouchQ

• Hypopituitarism (90%)
• Diabetes insipidus (10%)
• Growth retardation (50%)Q

• TranssphenoidalQ surgical resection followed by postoperative radiation
• Surgery alone is curative in less than half of patients because of recurrences due to adherence to vital structures or because of small tumor deposits in hypothalamus or brain parenchymaQ.

Cortisol (hydrocortisone)

Pituitary adenomaQ, Pituitary adenomas arise primarily from the anterior pituitary glandQ•

• Reticulin stainQ•
• Absence of reticulin stain in pituitary adenomaQ

• Dopamine agonist, bromocriptineQ, can shrink prolactinomas
• OctreotideQ can reduce GH levels

Sublabial or intranasal trans-sphenoidalQ approach

CraniopharyngiomaQ

Pituitary adenomaQ

Pituitary dependent cause of Cushing syndrome (pituitary adenoma secreting excessive ACTH)

MetastasisQ

Nerve sheath tumorQ

AstrocytomaQ

Intradural extramedullaryQ

• AIDS patients
• Transplant recipientsQ.

Its tendency for partial to complete resolution on CT after the administration of steroidsQ. Glucocorticoids should be withheld before biopsy due to cytolytic effect on lymphoma cells leading to nondiagnostic tissue.

High-dose methotrexateQ

Schwann cells superior vestibular nerve >Inferior vestibular (rarely cochlear)Q

MRI with gadolinium contrast Q

LauterbeurQ in 1973

Spectrum of symptoms and signs arising from an adrenocorticotropin (ACTH)–secreting pituitary macroadenoma after a therapeutic bilateral adrenalectomy.