Biochemistry Exam 1
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Evidence that rRNA is essential for Protein Synthesis
Single cleavage in 16S rRNA could block translation
23S rRNA essential for peptide bond formation
Antibiotics interact with rRNA NOT protein
RNA Polymerase Functions
- Scans DNA for initiation sites
- Unwinds short stretches of DNA (~17 bp)
- Selects nucleotides
- Catalyzes phosphodiester bond formation (5'-->3') at +1
- Interacts with regualtory proteins to regulate transcription
What are the ways to alter genes available for Transcription?
- Methylation of DNA
- Gene amplification
- Gene rearrangement
What would you like to do?
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