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  1. What you see in milk in mastitis
    • usually <100,000 cells in milk.  
    • mastitis = >>250,000, >99% WBC, almost all of those are neutrophils (= pus)
    • on average, infected cows have a higher somatic cell count (SCC), so we test this (decent height of both Sn and Sp)
  2. somatic cell count in milk
    • 200,000 cells is the cutoff
    • ~75% Sn, ~90% Sp
    • 95% confidence interval, even in end of days in milk with multiparous cows (who have highest uninfected counts)
  3. Milk loss is associated with linear score
  4. contagious mastitis MO
    Environmental mastitis MO
    • contagious: strep agalactiae, staph aureus, mycoplasma
    • environmental: strep, staph, coliforms
  5. drugs for mastitis and when to treat
    • systemic ceftiofur!  Could also do ampicillin, cephapirin, cloxacillin, hetacillin, penicillin, pirlimycin
    • fluids: Hypertonic saline + oral fluids
    • regional: moxi-mast in the quarter
    • if not systemically ill, WAIT IF POSSIBLE
    • saves $ on tx, prevents residues in tank, no abx resistance, sell more milk, 85% mild or moderate and delay doesn't hurt, wait and see. 
    • Some are sterile inflammation!
  6. 5 ways a cow can get mastitis
    • left front
    • right front
    • left hind
    • right hind
    • hematogenous spread (tiny proportion)
    • 99% are bacteria, caused inflammation. Often acquire infection at beg of dry period
    • KEEP THEM CLEAN.  This will lower mastitis!!
  7. reasons cows won't benefit from abx
    • choronic staph aureus
    • mycoplasma
    • multiple infected quarters
    • damaged teats
    • other serious metabolic disease
    • repeated previous tx failures
    • long history of chronically high SCC
    • grade 1 or 2 ecoli, enterobacter, yeast
    • truperella pyogenes
    • culture negative (25-30%)
    • SO ONLY TX: systemic e coli, strep, other staphs
    • Every farm is different, it's a cow-by-cow decision.  Most farmers guess, don't culture.
  8. reasons to pick a particular drug
    • frequency of administration (label!)
    • cost
    • withdrawal
    • availability
  9. up and down-sides of on-farm culturing
    • up: reference lab too far away
    • down: can't detect mycoplasma, prototheca difficult, staph aureus false positive risk, protocol drift, equipment maintenance and inventory, opportunity cost of valuable people's time (only a few people who are good at it)
  10. ups and downs of reference lab diagnostics
    • ups: experts do the work, ALL pathogens ID'd, quality control is daily, no maintenance or inventory, only training to take samples.  $5.50
    • downs: too far from lab, rely on someone else
  11. Bulk tank SCC count
    • done on composite bulk talk sample
    • multiple times/month
    • legal limit is 750,000 but no one takes over 400,000
  12. ***New infections are common in what stages of lactation?
    Calving and dry off
Card Set:
2017-11-09 16:59:17

Vb mastitis
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