WHAT HAPPENS IN SECRATORY DIARRHEA?
Cholera Toxin can constitiatively activate CFTR. If Cl is constantly moving into the lumen, so is water and Na is constantly following. SO you get intense diarrhea.
ORT – give them water, sugar, and salt.
Moving sugar across the gut is a Na dependent process so you move Na back into the basolateral side (rather than the lumen). Cl and water follow.