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what are the general characteristics of herpesvirus diseases?
- herpesviruses produce latent, recurrent, malignant diseases
- opportunistic to AIDS
where is the primary infection for HHV1 most common?
the ______of the HHV1 do not guarantee immunity to recurrent herpes
______ ______ serve as a reservoir for HHV1
HHV1 can have a re-occurrence because of what?
trauma-during dental procedures trauma can occure and bring about herpetic re-occurrences
what is a primary infection vs a full blown infections for primary herpetic gingivostomatitis?
- primary-mild or isolated lesions on the marginal or attached tissues
- full blown-oral ulcers
what are the frequent manifestations of HHV1?
gingivostomatitis and pharyngitis
what are the symptoms of HHV1?
- can't eat
- inflammation of lymph nodes
where do the oral vesicular lesions appear with HHV1?
what is trigeminal ganglia?
- Type of HHV1-subclinical carrier
- typical cold sore
what is herpes labialis?
- cold sore, fever blister
- HSV1 and HSV2
what triggers herpes labialis?
buring or slight stinging sensations with slight swelling that occurs before a local lesion occur.
where do herpes labialis occur?
- vermillion border
- gingiva or hard palate
what are the clinical characteristics of herpes labialis?
- group of vesicles-rupture or coalesces
- infectious lesion-with viral sheddign
- autoinfection-eye, nose, genitals, other people
what is herpetic whitlow?
herpes simplex infection of the fingers resulting from the virus entering thru minor skin abrasions
how is herpetic whitlow transmitted?
- HSV1 or HSV2
- primary or recurrent
- direct contact with vesicular lesion
- saliva contact
- autoinfection-nail biting
how can herpetic whitlow be prevented?
- standarded precautions
- nearly extinct
what is ocular herpes?
- herpes simplex lesion in the eye
how is ocular herpes transmitted?
- splashing of saliva
- extension from a facial lesion
- in utero, during birht
what are the symptoms of ocular herpes?
fever, pain, blurred vision, swelling, excess tears
what is herpes kertaconjunctionivitis (part of ocular herpes)?
deep inflammation-loss of sight
how can ocular herpes be prevented?
- standard precautions
- eye protection for the clinician and patient
what is herpes simplex virus 2?
where can HHV2 occur?
genitals, oral cavity, perioral infections
what is the clinical management of HHV2?
- patient history-thorough
- postpone appointments-explain to pt contagiousness and secondary infections
- irritation to lesions-prolong the course and increase the severity
- prodromal state-call and change appt when lesion is developing
what is the treatment for HHV2 and how is it used?
- acyclovir-antiviral drug
what is HHV3?
chickenpox and shingles
how is chicken pox transmitted?
- direct contact
- indirect contact
where does shingles lay latent?
dorsal root ganglia
what is the disease process of shingles? (2 types)
- localized unilateral-eruptions associated with the nerve endings of area innervated by infected sensory nerves
- introral lesions-when the second division of the trigeminal nerve is involved.
what is HHV4
Epstein-Barr Virus and hairy leucoplakia
what is Epstein Barr Virus?
what are the symptoms of EBV
- sore throat
what is the nickname for EBV
kissing disease-direct contact with saliva and by droplet
what is hairy leucoplakia associated with?
what are the symptoms of hairy leucoplakia?
white linear lesions along lateral borders
what is HHV5?
how is HCMV transmitted?
- exrected-urine, saliva, cervical secretions, semen
- blood transfusion
- post tranplant
- respiratory droplet
when is HCMV transmitted?
what are the childhood problems associated with HCMV?
- metal retardation
- motor disabilities
- chronic liver disease
what are the characteristics of HCMV in adults?
- serious complication of AIDS
how is HCMV prevented?
- personal hygiene
- standard precautions
- seropositivy check prior to surgeris
what is HHV6?
herpes lymphotrophic virus (HLV)
what are the characteristics of HLV?
- widespread-high % of people with antibodies
- depresses immune system
- latent indefinitely
what is a childhood infection of HLV?
roseola infantum-high temp and rash
when does HLV reactivate?
- bone marrow transplant
- solid organ transplant
- complicated by rejection of transplants
what are the characteristics of HHV7?
- prevalent in general population
- infection-bone marrow or solid organ transplant
what is the periodontal connection to HHV7?
high HHV7 in perio and in health tissues
what is HHV8?
Kaposi's Sarcome Related Virus
what is HHV8 a defining virus of?