Top 200 Drugs Part 2

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Author:
kitchenj
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36051
Filename:
Top 200 Drugs Part 2
Updated:
2010-12-21 15:40:07
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drugs MOA
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Part Two
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  1. propanolol
    • Brand Name: Inderal
    • Therapeutic Class: beta blocker
    • MOA: beta-blocker (aka beta-receptor antagonist)
  2. digoxin
    • Brand Name: Lanoxin
    • Therapeutic Class: antiarrhythmic agent
    • MOA: inhibits sodium-potassium ATPase
  3. glimepiride
    • Brand Name: Amaryl
    • Therapeutic Class: anitdiabetic agent
    • MOA: sulfonylurea, increases pancreatic insulin release
  4. vitamin d, ergocalciferol
    • Brand Name: Drisdol
    • Therapeutic Class: vitamin D, analog
    • MOA: synthetic vitamin D supplement
  5. ezetimibe and simvastatin
    • Brand Name: Vytorin
    • Therapeutic Class: antilipemic agent
    • MOA: cholesterol absorption inhibitor and HMG-CoA reductase inhibitor
  6. folic acid
    • Brand Name: Floacin
    • Therapeutic Class: vitamin
    • MOA: folic acid replacement
  7. cephalexin
    • Brand Name: Keflex
    • Therapeutic Class: antibiotic
    • MOA: cephalosporin: inhibits bacterial cell wall synthesis
  8. enalapril
    • Brand Name: Vasotec
    • Therapeutic Class: ACE inhibitor
    • MOA: ACE-I
  9. buspirone
    • Brand Name: BuSpar
    • Therapeutic Class: antianxiety agent
    • MOA: dopamine and serotonin agonist
  10. carbamazepine
    • Brand Name: Tegretol
    • Therapeutic Class: anticonvulsant
    • MOA: unknown
  11. losartan
    • Brand Name: Cozaar
    • Therapeutic Class: angiotensioin II receptor blocker
    • MOA: ARB
  12. methylphenidate
    • Brand Name: Ritalin
    • Therapeutic Class: CNS stimulant
    • MOA: CNS stimulant
  13. oxybutynin
    • Brand Names: Ditropan and Ditropan XL
    • Therapeutic Class: antispasmodic agent
    • MOA: anticholinergic, which causes the smooth muscle of the bladder to relax
  14. morphine
    • Brand Name: MS Contin
    • Therapeutic Class: analgesic
    • MOA: opioid receptor agonist
  15. ferrous sulfate
    • Brand Name: Feosol
    • Therapeutic Class: iron salt
    • MOA: iron supplement
  16. lidocaine transdermal
    • Brand Name: Lidoderm
    • Therapeutic Class: analgesic
    • MOA: stabilizes neuronal cell membranes by inhibiting fast-sodium channels
  17. carbidopa and levodopa
    • Brand Name: Sinemet
    • Therapeutic Class: anti-Parkinson's agent
    • MOA: carbidopa: inhibits the peripheral decarboxylation of levodopa, levodopa: DA receptor agonist
  18. tizanidine
    • Brand Name: Zanaflex
    • Therapeutic Class: alpha2-adrenergic agent
    • MOA: alpha-2 receptor agonist
  19. baclofen
    • Brand Name: Lioresal
    • Therapeutic Class: skeletal muscle relaxant
    • MOA: unknown
  20. verapamil
    • Brand Names: Isoptin and Calan
    • Therapeutic Class: antiarrhythmic agent
    • MOA: non-dihydropyridine (non-DHP) calcium channel blocker (CCB)
  21. ropinirole
    • Brand Name: Requip
    • Therapeutic Class: anti-Parkinson's agent
    • MOA: dopamine agonist
  22. metaxalone
    • Brand Name: Skelaxin
    • Therapeutic Class: skeletal muscle relaxant
    • MOA: unknown
  23. temazepam
    • Brand Name: Restoril
    • Therapeutic Class: benzodiazepine
    • MOA: binds to the receptors in the central nervous system (CNS)
  24. dicyclomine
    • Brand Name: Bentyl
    • Therapeutic Class: anticholinergic agent
    • MOA: anticholinergic agent and antispasmodic agent in the GI tract
  25. hydroxyzine pamoate
    • Brand Name: Vistaril
    • Therapeutic Class: antiemetic
    • MOA: H1 receptor blocker
  26. phenytoin
    • Brand Name: Dilantin
    • Therapeutic Class: anticonvulsant
    • MOA: enhances neuronal sodium efflux
  27. valsartan and hydrocholorthiazide
    • Brand Name: Diovan-HCT
    • Therapeutic Class: angiotensin II receptor blocker
    • MOA: valsartan: ARB, HCTZ: inhibits sodium and chloride reabsorption at the distal renal tubule
  28. fluconozole
    • Brand Name: Diflucan
    • Therapeutic Class: antifungal agent
    • MOA: inhibits fungal steroid production
  29. insulin (NPH)
    • Brand Name: Humulin
    • Therapeutic Class: insulin, intermediate-acting
    • MOA: synthetic insulin
  30. fluticasone (inhalation)
    • Brand Name: Flovent
    • Therapeutic Class: corticosteroid
    • MOA: inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
  31. amlodipine with benazepril
    • Brand Name: Lotrel
    • Therapeutic Class: ACE inhibitor
    • MOA: amlodipine: DHP CCB, benazepril: ACE-I
  32. acetaminophen with codeine
    • Brand Name: Tylenol with Codeine
    • Therapeutic Class: analgesic
    • MOA: codeine: opioid receptor agonists, acetaminophen: analgesic, MOA unknown
  33. oxcarbazepine
    • Brand Name: Trileptal
    • Therapeutic Class: anticonvulsant
    • MOA: unknown
  34. lithium
    • Brand Name: Lithobid
    • Therapeutic Class: antimanic agent
    • MOA: alters sodium transport in nerve and muscle cells resulting in intraneuronal metabolism of catecholamines, however the specific mechanism of action is unknown
  35. pramipexole
    • Brand Name: Mirapex
    • Therapeutic Class: anti-Parkinson's agent
    • MOA: DA receptor agonist
  36. nystatin (topical)
    • Brand Name: Nystop
    • Therapeutic Class: antifungal
    • MOA: binds to sterols in the fungal cell membrane, resulting in the cell membrane's inability to function as a selective barrier, thus allowing loss of essential constituents
  37. mometasone (intranasal)
    • Brand Name: Nasonex
    • Therapeutic Class: corticosteroid
    • MOA: inhibits phospholipase, prostaglandins, and leukotriene (mediators of inflammation)
  38. amoxicillin with clavulanate
    • Brand Name: Augmentin (XR)
    • Therapeutic Class: antibiotic
    • MOA: amoxicillin: beta lactam antibiotic; inhibits cell wall synthesis of mucopeptide, calvulanate: clavulanic acid: beta-lactamase inhibitor, which increases the antibacterial activity of beta-lactam antibiotic
  39. estradiol
    • Brand Name: Estrace
    • Therapeutic Class: estrogen derivative
    • MOA: estrogen supplement
  40. benazepril
    • Brand Name: Lotensin
    • Therapeutic Class: ACE inhibitor
    • MOA: ACE-I
  41. benzonatate
    • Brand Name: Tessalon
    • Therapeutic Class: antitussive
    • MOA: suppresses cough by anesthetizing the stretch receptors of the respiratory tract
  42. triamcinolone (topical)
    • Brand Name: Kenalog
    • Therapeutic Class: corticosteroid
    • MOA: inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
  43. ramipril
    • Brand Name: Altace
    • Therapeutic Class: ACE inhibitor
    • MOA: ACE-I
  44. levofloxacin
    • Brand Name: Levaquin
    • Therapeutic Class: antibiotic
    • MOA: quinolone antibiotic; inhibits bacterial DNA synthesis
  45. levetiracetam
    • Brand Names: Keppra and Keppra XR
    • Therapeutic Class: anticonvulsant
    • MOA: unknown
  46. ziprasidone
    • Brand Name: Geodon
    • Therapeutic Class: antipsychotic agent
    • MOA: selective DA and 5HT receptor antagonist
  47. insulin lispro
    • Brand Name: Humalog
    • Therapeutic Class: insulin, rapid-acting
    • MOA: synthetic insulin supplement
  48. gemfibrozil
    • Brand Name: Lopid
    • Therapeutic Class: antilipemic agent
    • MOA: increases activity of lipoprotein lipase
  49. methadone
    • Brand Name: Dolophine
    • Therapeutic Class: analgesic
    • MOA: opioid receptor agonist
  50. olmesartan
    • Brand Name: Benicar
    • Therapeutic Class: angiotensin II receptor blocker
    • MOA: ARB
  51. butalbital, acetaminophen, and caffeine
    • Brand Name: Fioricet
    • Therapeutic Class: barbiturate
    • MOA: acetaminophen: analgesic, MOA unknown, butalbital: causes sensory depression by inhibiting conduction in areas of the brain, caffeine: stimulate the CNS by increasing levels of cAMP
  52. methylprednisolone
    • Brand Name: Medrol
    • Therapeutic Class: corticosteroid
    • MOA: ?
  53. famotidine
    • Brand Name: Pepcid
    • Therapeutic Class: histamine H2 agonist
    • MOA: H-2 receptor antagonist
  54. eszopiclone
    • Brand Name: Lunesta
    • Therapeutic Class: hypnotic
    • MOA: agonist at GABA receptors in the CNS
  55. tramadol and acetaminophen
    • Brand Name: Ultracet
    • Therapeutic Class: analgesic
    • MOA: tramadol: binds to opioid receptor, also inhibits reuptake of NE and 5HT, acetaminophen: analgesic, MOA unknown
  56. methotrexate
    • Brand Names: Rheumatrex and Trexall
    • Therapeutic Class: antineoplastic agent
    • MOA: dihydrofolate reductase inhibitor (blocks conversion of dihydrofolate to tetrahydrofolate, thereby interfering with DNA synthesis
  57. sitagliptin
    • Brand Name: Januvia
    • Therapeutic Class: antidiabetic
    • MOA: DPPIV inhibitor (dipeptidylpeptidase IV inhibitor)
  58. doxazosin
    • Brand Name: Cardura (XL)
    • Therapeutic Class: alpha 1 blocker
    • MOA: alpha-1 receptor antagonist
  59. terazosin
    • Brand Name: Hytrin
    • Therapeutic Class: alpha 1 blocker
    • MOA: alpha-1 receptor antagonist
  60. olmesartan with hydrochlorothiazide
    • Brand Name: Benicar-HCT
    • Therapeutic Class: angiotensin II receptor blocker
    • MOA: olmesartan: ARB, HCTZ: inhibits sodium and chloride re-absorption at the distal renal tubule
  61. risedronate
    • Brand Name: Actonel
    • Therapeutic Class: biphosphonate derivative
    • MOA: osteoclast inhibitor
  62. sumatriptan
    • Brand Name: Imitrex
    • Therapeutic Class: antimigraine agent
    • MOA: 5HT-1 receptor agonist
  63. diphenoxylate with atropine
    • Brand Name: Lomotil
    • Therapeutic Class: antidiarrheal
    • MOA: antimuscarinic (blocks acetylcholine at the muscarinic receptors)
  64. meclizine
    • Brand Name: Antivert
    • Therapeutic Class: antiemetic
    • MOA: antihistamine
  65. benztropine
    • Brand Name: Cogentin
    • Therapeutic Class: anti-Parkinson's agent
    • MOA: anticholinergic (centrally acting)
  66. piroxicam
    • Brand Name: Feldene
    • Therapeutic Class: NSAID
    • MOA: ?
  67. clindamycin
    • Brand Name: Cleocin
    • Therapeutic Class: antibiotic
    • MOA: suppresses bacterial protein synthesis
  68. acyclovir
    • Brand Name: Zovirax
    • Therapeutic Class: antiviral agent
    • MOA: inhibits viral DNA replication
  69. nifedipine
    • Brand Name: Procardia
    • Therapeutic Class: calcium channel blocker
    • MOA: DHP CCB
  70. bumetanide
    • Brand Name: Bumex
    • Therapeutic Class: diuretic
    • MOA: "loop diuretic": blocks sodium and chlorine re-absorption from kidney tubules
  71. solfenacin
    • Brand Name: Vesicare
    • Therapeutic Class: anticholinergic agent
    • MOA: muscarinic receptor antagonist
  72. quinapril
    • Brand Name: Accupril
    • Therapeutic Class: ACE inhibitor
    • MOA: ACE-I
  73. levonorgestrel with ethinyl estradiol (triphasic)
    • Brand Name: Triphasil
    • Therapeutic Class: contraceptive
    • MOA: ethinyl estradiol: estrogen receptor agonist, levonorgestel: progesterone receptor agonist
  74. rosiglitazone
    • Brand Name: Avandia
    • Therapeutic Class: antidiabetic agent
    • MOA: peroxisome proliferator-activated receptor (PPAR) gamma agonist
  75. promethazine with codeine
    • Brand Name: Phenergan with codeine
    • Therapeutic Class: analgesic
    • MOA: promethazine: H1 receptor blocker, codeine: opioid receptor agonist
  76. glyburide with metformin
    • Brand Name: Glucovance
    • Therapeutic Class: antidiabetic
    • MOA: glyburide: sulfonylurea, increases pancreatic insulin release, metformin: main effect believed to inhibition of hepatic gluconeogenesis
  77. insulin
    • Brand Name: Novolin
    • Therapeutic Class: insulin, intermediate-acting
    • MOA: synthetic insulin
  78. norgestimate with ethinyl estradiol
    • Brand Name: Ortho Tri-Cyclen
    • Therapeutic Class: contraceptive
    • MOA: progesterone and estrogen receptor agonists, respectively
  79. olanzapine
    • Brand Name: Zyprexa
    • Therapeutic Class: antimanic agent
    • MOA: unknown, believed to antagonize effects of DA and 5HT
  80. drospirenone with ethinyl estradiol (21)
    • Brand Name: Yasmin
    • Therapeutic Class: contraceptive
    • MOA: progesterone ad estrogen receptor agonists, respectively
  81. diclofenac
    • Brand Name: Voltaren
    • Therapeutic Class: NSAID
    • MOA: ?
  82. dipyridamole and aspirin
    • Brand Name: Aggrenox
    • Therapeutic Class: antiplatelet agent
    • MOA: dipyridamole: inhibits the uptake of adenosine into platelets, endothelial cells and erthyrocytes, aspirin: irreversible inhibitor of cyclo-oxygenase enzymes 1 and 2
  83. ibandronate
    • Brand Name: Boniva
    • Therapeutic Class: biphosphonate derivative
    • MOA: osteoclast inhibitor
  84. prochlorperazine
    • Brand Name: Compazine
    • Therapeutic Class: antiemetic
    • MOA: inhibits the DA receptors in the medullary chemoreceptor trigger zone and peripherally by blocking the vagus nerve in the gastrointestinal tract
  85. mupirocin
    • Brand Name: Bactroban
    • Therapeutic Class: antibiotic
    • MOA: inhibits bacterial protein synthesis
  86. nitrofurantoin
    • Brand Names: Macrodantin and Macrobid
    • Therapeutic Class: antibiotic
    • MOA: inhibits bacterial carbohydrate metabolism
  87. clotrimazole with betamethasone
    • Brand Name: Lotrisone
    • Therapeutic Class: antifungal agent
    • MOA: increase permeability of fungal cell wall
  88. metrondiazole
    • Brand Name: Flagyl
    • Therapeutic Class: amebicide
    • MOA: causes bacterial DNA strand breakage
  89. methocarbamol
    • Brand Name: Robaxin
    • Therapeutic Class: skeletal muscle relaxant
    • MOA: unknown and presumed to be due to general CNS depression
  90. chlorpheniramine with hydrocodone
    • Brand Name: Tussionex
    • Therapeutic Class: analgesic
    • MOA: chlorpheniramine: H2 receptor antagonist, hydrocodone: opioid receptor agonist
  91. raloxifene
    • Brand Name: Evista
    • Therapeutic Class: selective estrogen receptor modulator (SERM)
    • MOA: SERM
  92. modafinil
    • Brand Name: Provigil
    • Therapeutic Class: stimulant
    • MOA: unknown; CNS-activating agent
  93. sucralfate
    • Brand Name: Carafate
    • Therapeutic Class: GI agent
    • MOA: exact mechanism of action is not known; however, sucralfate is thought to form an ulcer-adherent complex with proteinaceous exudate, such as albumin and fibrinogen, at the ulcer site, protecting it against further acid attack
  94. darifenacin
    • Brand Name: Enablex
    • Therapeutic Class: anticholinergic agent
    • MOA: muscarinic receptor antagonist
  95. niacin (extended-release)
    • Brand Name: Niaspan
    • Therapeutic Class: antilipemic agent
    • MOA: enhances lipoprotein lipase activity
  96. azelastine (nasal)
    • Brand Name: Astelin
    • Therapeutic Class: histamine H1 agonist
    • MOA: selective H1-receptor antagonist
  97. nabumetone
    • Brand Name: Relafen
    • Therapeutic Class: NSAID
    • MOA: ?
  98. valacyclovir
    • Brand Name: Valtrex
    • Therapeutic Class: antiviral agent
    • MOA: inhibits viral DNA replication
  99. thyroid, dessicated
    • Brand Name: Armour Thyroid
    • Therapeutic class: thyroid product
    • MOA: thyroid hormone supplement
  100. ondansetron
    • Brand Name: Zofran
    • Therapeutic Class: antiemetic
    • MOA: selective 5-hydroxytryptamine-3 (5-HT3)- receptor antagonist

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