Ch 19 The Body and Drugs
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study of how drugs produce their effects on desired cells and how a drug is processed by the body; study of biochemical and physiolofic effects of drugs and their mechanisms of action
general term referring to a large number of cells, all of which are similar, on which a particular drug is intended to act
an interaction between two or more drugs administered to a patient, resulting in either an increas or a decrease in the therapeutic effects of one or more of the drugs, or an adverse effect.
any substance produced by the metabolic process
study of the time course of a drug and its metabolites in the body following drug administration
process by which a drug is moved from the site of administration into the bloodstream
process by which an absorbed drug is moved from the bloodstream to body tissues or receptors
passive transport across a cell membrane; drug molecules move from an area of high concentration into an area of low concentration
carrier protein permits specific molecules to pass through certain parts of the cells, requires energy
- certain substances are permitted to accumulate outside the cells
- the accumulation generates concentration gradient that will permit transportaion of substance from outside the cell into the cell
the cell engulfs substance and permits substance to enter the cell, requires energy
degree to which a drug becomes available to body tissues after administration
pattern of compulsive substance abuse characterized by continued psychological and physiological craving or need for the substance and its effects
when a person requires (psychologically or physiolofically) larger doses of a drug to achieve same effect
state of being dependent
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