MedMicro

Card Set Information

Author:
BigMig
ID:
37610
Filename:
MedMicro
Updated:
2010-09-27 01:27:53
Tags:
Immunoglobulins
Folders:

Description:
Delayed-Type Hypersensitivity Reactions / Immunoglobulins
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  1. Jones-Mote
    • 24hr
    • Skin Swelling
    • Basophils, Lymphocytes, Mononuclear cells
    • Intradermal Ag, Ovalbumin
  2. Contact
    • 48hr
    • Eczema
    • Mononuclear cells, Edema, Raised epidermis
    • Epidermal: nickel, rubber, poison ivy
  3. Tuberculin
    • 48 hr
    • Local induration and swelling w/wo fever
    • Mononuclear cells, lymphocytes and monocytes, reduced macrophages
    • Dermal: Tuberculin, Mycobacterial, and leishmanial
  4. Granulomatous
    • 4 wk
    • Skin induration
    • Epithelioid cell granuloma, giant cells, macrophages, fibrosis w/wo necrosis
    • Persistent Ag or Ag-Ab camplexes in macrophages or "nonimmunologic"
  5. IgM
    • T ind & TH1
    • Serum
    • Resist: Preciptin, Primary response
    • Complement Fixation
    • Pentameric (J chains)
  6. IgD
    • Receptor for B cells
    • B-cell Activation
  7. IgG
    • TH1, TH2
    • Abundant
    • Serum, Tissue
    • Resist: Opsonin, secondary response
    • Complement Fixation
    • Opsonin for macrophage, PMN
    • Crossing of placenta
  8. IgE
    • TH2
    • Mast Cells
    • Anaphylaxis
  9. IgA
    • TH2
    • secretions
    • Resist: Protection of mucous membranes
    • Complement Fixation
    • Mucosal Secretions
    • Monomeric (monomers, dimers, trimers, multimers - J chains)

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