Path Q1 lab inflammation

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Path Q1 lab inflammation
2010-09-27 17:25:22
Path Q1 lab inflammation

Path Q1 lab cellular inflammation
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    • Chronic inflammation in synovium of patient with rheumatoid arthritis
    • Collections of dark blue lymphocytes seen
    • Dark area = lymphoid aggregate
    • pink area near lymphoid aggregate= fibrosis
    • Gallbladder in patient with cholecystitis
    • Neurotrophils seen infilitrating mucosa
    • Columnar epithelial cells seen
    • Neurophils mainly, but allso plasma cells, lymphocytes, macrophages seen in this inflammatory reaction
    • Big macrophages seen
    • Vasodilation with exudation --> outpouring of fluid with fibrin into alveolar spaces, along with PMNs
    • In exudation, fluid, proteins, RBCs, WBCs enter extravascular space
    • Vascular stasis
    • Fibrin mesh in fluid with PMNs
    • This fluid collection produces "tumor" or swelling
    • Extensive neurophil exudate of abscessing pneumonia
    • Normal tissue destroyed in the abscess region (necrotizing pattern of inflammation)
    • Granulation tissue (capillaries, fibroblasts, inflammatory cells)
    • Endolthelial cells plump
    • Aspiration penumonia
    • Giant cell seen at upper left part of vegetable matter
    • Foreign body giant cells ahve nuclei scattered haphazardly around cell
    • Suture material seen
    • 2 foreign body giant cells seeen just to the right of the center where there is a bluish strand from a previous operation
    • Prroly formed granuloma
    • Lung of patient with influenza A
    • Inflammatory infiltrates of chronic inflammation are more likely to be interstitial (within tissues) rather than exudateive (above suraces or spaces) like in acture inflammation
    • Thickened alveolar walls seen
    • Lymphocytes within alveolar walls
    • Non-caseating granuloma (2)
    • Contains giant cells, epithelioid macrophages, lymphocytes, plasma cells, fibroblasts
    • Silicotic nodule in lung
    • Dense pink collagen seen in center of nodule (=scar)
    • Bronchopneumonia in lung
    • PMNs seen in alveoli
    • Neutrophilic alveolar exudate seen --> productive cough
    • Talc seen in patient who was an IV drug abuser
    • Foreign material can produce granulomatous reaction
  1. Epitheliod cells around center of granuloma seen (contains lots of pink cytoplasm, nucleus tend to be long and stringy)
    • Wall of abscess has granulation tissue
    • Prurlent exudate with some hemorrhage is seen at righ in abscess center
    • Vasculitis seen - descruction accompanying acute inflammation, coagulation involved
    • Arterial wall undergoing necrosis
    • Thromcus in lumen
    • Black dots in wall of vessel indicates inflammation
    • Inflammatory cells surrounding thrombus (lower right)
    • Vasculitus with arterial wall necrosis
    • Neutrophilic nucelei have fragmented
    • Re-epithelialization seen on skin surface
    • Granulation tissue seen below (small capillaries and fibroblasts seen)