BIOCHEM: TCA Cycle

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Author:
vsanche4
ID:
39788
Filename:
BIOCHEM: TCA Cycle
Updated:
2010-10-04 21:18:52
Tags:
TCA
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Description:
TCA Cycle
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  1. (2) Pyruvate + Acetyl CoA ---> Citrate
    Citrate Synthase

    G= -7.7
  2. Citrate ----> Isocirate
    Aconitase

    G= +1.5
  3. Isocitrate --->alpha-ketoglutarate
    Isocitrate dehydrogenase

    • NAD+ ---> NADH
    • ----->C02

    G=-5.3
  4. Alpha-ketoglutarate ---->Succinyl CoA
    Alpha-ketoglutarate

    • NAD+ ----> NADH
    • -----> CO2

    G=-8.0
  5. Succinyl CoA ----> Succinate
    Succinate Thiokinase

    • GDP + Pi ---> GTP
    • -----> CoA

    G=-0.7
  6. Succinate -----> Fumarate
    Succinate Dehydrogenase

    FAD ----> FAD(H2)

    G=0
  7. Fumarate -----> Malate
    Fumerase

    <----H20

    G=0
  8. Malate -----> Oxaloacetate
    Malate Dehydrogenase

    NAD+ ---> NADH H+

    G=+7.1

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