Alpha Blockers

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Author:
Kristin
ID:
40759
Filename:
Alpha Blockers
Updated:
2010-10-14 19:11:49
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Drug Cards
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  1. What is an ARB?
    Angiontensin II Receptor Blocker
  2. What receptor does ARB drugs block?
    AT1 receptor
  3. Why are ARBs not assosiated as much with cough side effects as the ACE inhibitors are?
    They do not effect break down of bradykinin
  4. What patients are reccomended to take ARBs?
    Ones who are having good results with their ACE inhibitors but are getting the cough side effect from it?
  5. What is the crossover Angioedema Risk?
    3-8%
  6. What is the ARB mechanism of action?
    they block the action of angiotensin II
  7. What is the drug class and the brand name for losartan?
    Cozaar; angiotensin II receptor blocker
  8. What is the drug class and the brand name for valsartan?
    Diovan; angiotensin II receptor blocker
  9. What is the drug class and the brand name for Irbesartan?
    Avapro; angiotensin II receptor blocker
  10. What is the drug class and the brand name for Candesartan?
    Atacand; angiotensin II receptor blocker
  11. What is the drug class and the brand name for Olmesartan?
    Benicar; angiotensin II receptor blocker
  12. Who are Alpha 1-Receptor Blockers primarily used for and What is their purpose?
    Primarily used in men and they are for the treatment of high blood pressure and the treatment of BPH
  13. Alpha 1-receptor blockers are not used first line unless treating...
    ...patients with high blood pressure and BPH
  14. What is BPH?
    Benign prostatic hyperplasia
  15. What is the mechanism for alpha 1-receptor blockers?
    they block the alpha 1-receptors of vascular smooth muscle, thus preventing the reuptake of catecholamines by the smooth muscle cells
  16. Where are alpha-1 receptors mainly found?
    prostate
  17. What does blocking the catecholines cause?
    vasodilation and allows blood to flow more easily
  18. what are catecholamines, where are derived from, and where are they found?
    chemical compounds, derived from amino acids, and found circulating in the blood
  19. What are catecholines assosiated with?
    stress
  20. what do catecholines do to BP and HR?
    increase blood pressure and increase heart rate
  21. What are some examples of catecholamines?
    epinephrine, nor-epinephrine, and dopamine
  22. What is the drug class and the brand name for doxazosin?
    alpha 1-receptor blocker; cardura
  23. What is the drug class and the brand name for terazosin?
    alpha 1-receptor blocker; hytrin
  24. Why are alpha 1-receptor blockers normally used in combination?
    there is difficulty in lowering blood pressure (not very effective by itself)
  25. What are some of the adverse side effects of alpha 1-receptor blockers and what is some patient education for this medication?
    adverse effect: palpitations, nausea, and headache; patient education: take first dose at bedtime
  26. What are some of the adverse side effects of doxazosin and what is some patient education for this medication?
    adverse effect: palpitations, nausea, and headache; patient education: take first dose at bedtime
  27. What are some of the adverse side effects of terazosin and what is some patient education for this medication?
    adverse effect: palpitations, nausea, and headache; patient education: take first dose at bedtime. do not take if pregnant (woman)
  28. What are some of the adverse side effects of valsartan and what is some patient education for this medication?
    adverse effect: dizziness, increase K+, hypotension; patient education: do not take if pregnant (woman), caution while driving due to possible dizziness
  29. What are some of the adverse side effects of irbesartan and what is some patient education for this medication?
    adverse effect: dizziness, increase K+, hypotension; patient education: first dose to be taken at bedtime, caution while driving due to possible dizziness
  30. What are some of the adverse side effects of candesartan and what is some patient education for this medication?
    adverse effect: dizziness, increase in K+ levels, hypotension; patient education: take preferably on empty stomach (1 hour before or 2 hours after), caution while driving due to possible dizziness
  31. What are some of the adverse side effects of olmesartan and what is some patient education for this medication?
    adverse effect: dizziness, increase in K+ levels, hypotension; patient education: do not use potassium supplement or salt subsitutes, caution while driving due to possible dizziness
  32. What is the drug class and the brand name for clonidine?
    aplha-2 agonist; Catapres
  33. What's the mechanism for clonidine?
    crosses the blood brain barrier and selectively stimulates receptors in the brain that monitor catecholamine levels in the blood
  34. How does clonidine work? What does it do?
    it activates an inhibitory neuron and decreases sympathetic outflow therefore there is a decrease in catecholamine production, decrease in HR and decrease in BP.
  35. What are some of the side effects associated with clonidine? What is the patient education?
    dry mouth, drowsiness, dizziness, headache; edu: take with food or milk, change transdermal skin sites with each application of patch
  36. What can clonidine be used for?
    migraine headache, symptoms associated with menopause or menstrual discomfort, symptoms of withdrawal associated with alcohol, nicotine, or narcotics, ADHD, high blood pressure
  37. What is the generic name for Avalide?
    Irbesartan and HCTZ
  38. What is the generic name for Hyzaar?
    Losartan and HCTZ

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