Lab Diagnosis of Cancer
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define incisional biopsy
portion of lesion taken for microscopic examination
define excisional biopsy
entire lesion was removed for microscopic examination
define frozen section biopsy
done at time of surgery. quick but prone to errors.
define electron microscope biopsy
requires special fixative and is useful in an extremely limited number of cases
define fine needle aspiration biopsy
useful in evaluating superficial and deep-seated masses
define cytologic (papanicolaou) smears
screening method for cervical cancer and HPV
specific antibody-guided detection of tumor-specific/assoc. antigens to determine classification of a tumor
define flow cytometry
routinely used in classifying leukemias and lymphomas. surface markers and dna ploidy analysis
define biochemical assay
looking for tumor-associated enzymes, hormones and other markers in the blood. prostate-specific antigen is a good exmaple.
define molecular diagnosis
use of FISH or PCR
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